Depression News and Research

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Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

New technique could accelerate drug research for various diseases

Alicyclic compounds are groups of organic chemical compounds that have led to the development of a number of medications.

19 Aug 2020

Study: Transgender and gender-diverse adults more likely to be diagnosed as autistic

Transgender and gender-diverse adults are three to six times more likely as cisgender adults (individuals whose gender identity corresponds to their sex assigned at birth) to be diagnosed as autistic, according to a new study by scientists at the University of Cambridge's Autism Research Centre.

10 Aug 2020

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

A world first clinical study of the gut microbiome in people with Huntington's disease (HD) has found that it is not just a disease of the brain, but also of the body.

7 Aug 2020

Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

4 Aug 2020

Phthalate exposure associated with sleep disruptions in midlife women

For menopausal women who have difficulty sleeping, it might be because of chemicals in the environment.

30 Jul 2020

Study estimates the cost-effectiveness of esketamine used for treating depression

A paper authored by researchers from McLean Hospital has determined that esketamine, a nasal spray to treat severe depression, is currently too expensive for widespread use.

14 Jul 2020

NCCN Distress Thermometer translated into 46 languages for global accessibility

The National Comprehensive Cancer Network--an alliance of leading cancer centers in the United States--today announced the NCCN Distress Thermometer has been translated into 46 languages.

14 Jul 2020

Researchers track how key brain receptor works

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals.

1 Jul 2020

New LI383 molecule can help treat opioid-related disorders

A novel molecule LIH383 developed by scientists at the Luxembourg Institute of Health binds to and inhibits a formerly unknown opioid receptor in the brain.

22 Jun 2020

Fish Oil May Help With Depression

A study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

17 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020

Study uncovers two brain phenomena that may explain ketamine's side-effects

Researchers have identified two brain phenomena that may explain some of the side-effects of ketamine. Their measurements of the brain waves of sheep sedated by the drug may explain the out-of-body experience and state of complete oblivion it can cause.

12 Jun 2020

Study uncovers new risk genes for problematic alcohol use

Do you have what is known as problematic alcohol use? Then statistically you will also be particularly genetically predisposed to develop e.g. depression and insomnia. And to become dependent on drugs and tobacco. This is shown by a new international study in which researchers from iPSYCH are involved.

8 Jun 2020

Researchers evaluate long-term impact of bighorn sheep translocations

Translocation is an important management tool used for nearly 100 years to increase bighorn sheep population numbers in Wyoming and to restore herds to suitable habitat throughout their historical range. Y

4 Jun 2020

Synthetic molecule suppresses drug cravings with fewer side effects

A new synthetic molecule selectively reduces the physiological rewards of cocaine in mice.

1 Jun 2020

Researchers identify 29 genetic variants linked to problematic drinking

Scientists carried out a genome-wide analysis of over 435,000 people, revealing 29 genetic variants associated with problematic drinking.

27 May 2020

What If We Could Design Powerful Drugs Without Unwanted Side Effects?

Psychedelics have proven effective in treating depression and PTSD, but the medical use of these drugs is limited by their hallucinations.

22 May 2020

Scientists develop computer model to accurately predict brain age

Scientists have trained a computer to analyze different types of brain scan and predict the age of the human brain, according to a new study in the open-access journal eLife.

20 May 2020

Eating one meal high in saturated fat may affect our ability to focus

Fatty food may feel like a friend during these troubled times, but new research suggests that eating just one meal high in saturated fat can hinder our ability to concentrate - not great news for people whose diets have gone south while they're working at home during the COVID-19 pandemic.

19 May 2020

Cholesterol Lowering Drugs Linked To Improved Gut Bacteria Composition In Obese People

The human gut microbiota consists of bacteria, fungi, and viruses constituting an inner chemical factory producing a multitude of microbial compounds.

7 May 2020