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Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

Study shows why obese mothers tend to have children susceptible to metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop the metabolic disease during their lifetime, as suggested by previous research.

27 Jan 2021

Researchers identify a vital protein needed to regulate anti-tumor immune response

Scientists from The University of Texas MD Anderson Cancer Center have identified a protein known as NF-kappa B-inducing kinase (NIK).

5 Jan 2021

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

22 Dec 2020

Biochemical methods reveal signal transduction mystery inside human pathogen

In order to adapt to the changing environment, bacteria must quickly transform extracellular information into appropriate intracellular reactions. Two component system (TCS) is the main signal transduction protein in prokaryotic cells to transform environmental stimuli into cellular responses.

16 Dec 2020

Repair proteins can help healthy cells to avoid damage during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

10 Dec 2020

Study reveals metabolic signaling pathways that influence key immune cells

Effector regulatory T cells, also known as eTreg cells, are a specialized subset of white blood cells that maintain the immune system.

18 Nov 2020

Researchers identify key target to prevent viruses from disarming the human immune response

Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections.

11 Nov 2020

Study sheds new light on key protein implicated in tumor development

A study headed by the University of Colorado Boulder has revealed a specific protein that is crucial for regulating the growth, proliferation, and function of cells, and how these cells were long implicated in the development of tumors.

5 Nov 2020

Similarities between animal and plant immune systems go beyond sensing

Max Planck Institute for Plant Breeding Research (MPIPZ) and University of Cologne researcher Takaki Maekawa and colleagues have discovered that plants have independently evolved a family of immune proteins that are strikingly similar to animals.

3 Nov 2020

Researchers describe how drug use change specific brain cells responsible for motivation

In the October 28, 2020 issue of the Journal of Neuroscience, researchers from the Medical University of South Carolina and the National Institutes of Health describe how reminders of drug use can change specific brain cells responsible for motivation, increasing the desire to seek drugs.

30 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Study discusses the role of insects as a potential new food allergen

Those with food allergies must avoid allergens in food. Health problems can be triggered by even the smallest traces for those affected. This is why manufacturers of ready-made foods must list the ingredients on the packaging.

21 Oct 2020

New tool can provide non-invasive decision support for treating lung cancer

Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related death worldwide, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors.

19 Oct 2020

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib.

7 Oct 2020

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020