Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Novel adoptive T cell receptor therapy shows promising results for patients with solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

30 Jan 2023

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

27 Jan 2023

Persistent tumor mutation load may help predict outcome of novel immunotherapies

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

27 Jan 2023

MicroRNA’s influence on lupus disease inflammation

Researchers from Nagoya University’s Graduate School of Medicine in Japan have uncovered how microRNA (miRNA) affects inflammation in mice with lupus. They discovered two downregulated miRNAs in the disease along with a rare circumstance where several miRNAs control the same set of genes.

27 Jan 2023

Tumor progression after immunotherapy: Molecular pathways revealed

The University of Michigan’s Rogel Cancer Center researchers discovered a mechanism that explains why a subset of patients’ tumors grows rather than shrink when treated with immunotherapy.

20 Jan 2023

New gene helps drive the development of the common lung cancer type

At the NYU Langone Health’s Perlmutter Cancer Center, a team headed by scientists has determined a gene that forces the development of the second most common type of lung carcinoma.

From New York University (NYU) 11 Jan 2023

Major development in re-treatment with CAR T therapy

At the American Society of Hematology (ASH) Annual Meeting in 2022 (Abstract 2016), researchers from the Abramson Cancer Center at the University of Pennsylvania presented preliminary findings from an ongoing Phase I clinical trial demonstrating effective re-treatment with CAR T cell therapy for patients whose cancers relapsed after prior CAR T therapy.

12 Dec 2022

Predictive classifier identifies patients who can skip radiation therapy

According to the findings of a meta-analysis proposed at the San Antonio Breast Cancer Symposium held on December 6–10th, 2022, patients with invasive breast cancer who had low scores on an investigational gene molecular signature seemed to have similar rates of local recurrence regardless of whether they received adjuvant radiation therapy after breast-conserving surgery.

12 Dec 2022

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Mutations in the BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 persons, respectively, elevate the risk of various malignancies such as ovarian, breast, pancreatic, and prostate cancer considerably.

30 Nov 2022

Regeneration of the immune system in MS patients

Transplanting blood stem cells is a new but incredibly successful treatment for multiple sclerosis. Now, a study directed by the University of Zurich has looked closely at how the autoimmune disease is controlled by the treatment and how the immune system recovers afterward.

14 Nov 2022

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

PacBio announces the commencement of external beta testing of the Onso Sequencing System

PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced the commencement of external beta testing of the Onso™ Sequencing System. This innovative benchtop short-read DNA sequencing platform is expected to provide an extraordinary level of accuracy by utilizing PacBio’s unique sequencing by binding (SBB) technology.

26 Oct 2022

UC Davis launches new center to accelerate the development of promising cancer therapies

UC Davis Comprehensive Cancer Center has launched a Center for Experimental Therapeutics in Cancer to accelerate promising cancer therapies from the lab to the bedside.

From The University of California, Davis 10 Oct 2022

MD Anderson and Virogin Biotech collaborate to advance the development of investigational oncolytic viruses, treatments

The University of Texas MD Anderson Cancer Center and Virogin Biotech today announced a strategic collaboration to accelerate the development of investigational treatments, including oncolytic viruses and immunotherapies, for patients with advanced cancers.

12 Sep 2022

Simple blood test helps identify patients developing neurotoxic side effects

The treatment of various tumors has been transformed by cell-based immunotherapy, often known as CAR-T cell therapy. To target and combat specific forms of leukemia and lymphoma, the treatment employs genetically engineered T cells.

8 Sep 2022

Study explains the dynamics underlying liver damage

The immune system may attack the liver when fat builds up there. The chemical that triggers these responses has been discovered by Weill Cornell Medicine researchers in a recent study, and this information helps to explain the dynamics of liver damage that can accompany type 2 diabetes and obesity.

23 Aug 2022

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

As a result of this partnership, Inventia Life Science will now offer BioLamina’s extensive range of Biolaminin® products incorporated into the pre-validated library of RASTRUM™ Matrices, recapitulating the key motifs found in the native tissue of various cell types.

From Inventia Life Science 16 Aug 2022

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Inventia Life Science, a leader in automated generation of complex 3D cell models, and PhenoVista Biosciences, a top provider of custom imaging-based phenotypic assay services, have entered into a partnership to deliver high-content cell-based assay services for drug discovery.

From Inventia Life Science 16 Aug 2022

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

State-of-the-art laboratories significantly expand project capacity to meet increasing market demand for Organ-on-a-Chip research services.

From CN Bio Innovations Limited 19 Jul 2022

Researchers analyze the significance of cellular interactions for lung cancer

A new Cleveland Clinic study has uncovered vital information about the cellular interaction of tumor cells and normal tissue, leading to a better understanding of how therapeutic resistance evolves.

5 Jul 2022

Oncology News and Research

Novel adoptive T cell receptor therapy shows promising results for patients with solid tumors

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

Persistent tumor mutation load may help predict outcome of novel immunotherapies

MicroRNA’s influence on lupus disease inflammation

Tumor progression after immunotherapy: Molecular pathways revealed

New gene helps drive the development of the common lung cancer type

Major development in re-treatment with CAR T therapy

Predictive classifier identifies patients who can skip radiation therapy

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Regeneration of the immune system in MS patients

New bioprinting platform to replicate tumors in 3D spheroids

PacBio announces the commencement of external beta testing of the Onso Sequencing System

UC Davis launches new center to accelerate the development of promising cancer therapies

MD Anderson and Virogin Biotech collaborate to advance the development of investigational oncolytic viruses, treatments

Simple blood test helps identify patients developing neurotoxic side effects

Study explains the dynamics underlying liver damage

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

Researchers analyze the significance of cellular interactions for lung cancer

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