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Unraveling the Mystery of L-Cry: A Distinctive Cryptochrome Protein

In a recent release in Nature Communications, a collaborative research group comprising Johannes Gutenberg University Mainz (JGU), the University of Cologne, and the University of Oldenburg has disclosed their discoveries regarding the operation of a distinctive cryptochrome protein (Cry).

16 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Distinctive Taste Receptors Between a Moth’s Larval and Adult Stages

New research reveals that the cotton bollworm (Helicoverpa armigera) employs distinct sugar-sensing mechanisms in its larval and adult stages to fulfill its dietary preferences.

8 Nov 2023

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

7 Nov 2023

Novel Gene Therapy Targets Core Motor Symptoms of Parkinson’s Disease

A team of researchers from the Shenzhen Institute of Advanced Technology (SIAT) at the Chinese Academy of Sciences (CAS) and their collaborators have devised a gene therapy approach aimed at selectively manipulating the affected circuitry in Parkinson’s disease.

6 Nov 2023

Dendritic Cells Reprogram Their Genes to Enhance Immune Response

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), under the leadership of Professor Francisco Sánchez-Madrid, have discovered that dendritic cells, responsible for triggering targeted immune responses, possess the ability to modify their genes in order to enhance their immune reactivity.

6 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

ISB Researchers Discover Genetic Key to T Cell Development

T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory – remembering the specific pathogens or the cancer signatures that originally trigger T cells.

26 Oct 2023

Engineering Plants to Turn Red in the Presence of Toxic Pesticide

Imagine if houseplants could alert one to unsafe water conditions. Scientists are making strides toward this innovative idea by successfully modifying a plant to change its color to beet red when it detects the presence of a prohibited and harmful pesticide.

24 Oct 2023

The Exclusome, A New Mammalian "Container"

We speak to Dr. Ruth Kroschewski about new research that details the existence of an 'exclusome', a cytoplasmic container that appears to explain where extra-chromosomal DNA goes once it is in a cell.

24 Oct 2023

Study Offers Fresh Insights into Immune System Proteins

A new study from the USC Michelson Center for Convergent Bioscience’s Bridge Institute, in partnership with multinational teams from India, Australia, and Switzerland, sheds insight on these proteins.

18 Oct 2023

Breakthrough Research Discovers How the Body Controls Itch

It can be a relief to scratch the occasional itch, but when itch gets out of control, it can become a serious health problem. How does the body know when to stop?

16 Oct 2023

Lactate Oxidase Nanocapsules Help the Immune System to Fight and Kill Solid Tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

13 Oct 2023

Effectiveness of SCID-X1 Gene Therapy Influenced by 3D Genome Architecture

Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), often known as “bubble boy disease,” are born with a faulty gene that inhibits immune cells from being produced.

9 Oct 2023

Regulator Gene for Intestinal Stem Cells Discovered

When a cell dies, a new one has to be formed in its place. This is a regular occurrence in the intestines, where cells are especially exposed to harmful effects.

9 Oct 2023

The Astute White Blood Cell Defense

Neutrophils, the most prevalent kind of white blood cell, are able to block Candida albicans toxin, according to study from Umeå University. EMBO Reports has published the findings.

6 Oct 2023

Immune Cells Can Create Their Own Chemical Cues to Navigate

In a breakthrough finding, Jonna Alanko, a researcher from InFLAMES, has unveiled that immune cells are not mere passive followers of chemical signals in their surroundings.

7 Sep 2023

Targeted MicroRNA-34a Therapy Shows Promise in Slowing Tumor Growth in Mice

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.

5 Sep 2023