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Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

Sensing and communicating with the extracellular environment are both aspects of transmembrane signaling.

24 Jul 2023

New Approach to Reverse Aging and Restore Cellular Function

Researchers have opened a new front in the battle against aging and diseases associated with old age through a ground-breaking study

13 Jul 2023

New Gene Discovery Could Revolutionize Sex Determination in Green Algae

An international team of researchers led by Dr. James Umen at the Donald Danforth Plant Science Center has made a groundbreaking discovery in the world of developmental biology.

13 Jul 2023

The Mechanism of Immune Memory Development

The memory of the immune system depends on distinctive epigenetic traits and a particular 3D arrangement of the DNA in the nucleus of memory cells, allowing for rapid activation of these cells, according to a team of researchers from the Erasmus University Medical Center, the Centre for Genomic Regulation (CRG), and the Josep Carreras Leukaemia Research Institute.

12 Jul 2023

New Insights Into How Genes Are Activated

Genetic information contained within DNA has to be read by specific proteins that enable the process of gene activation to begin – but in many cases, these proteins can't access their targets because DNA strands are bundled up to control what genes are used in the wide range of different cell types.

12 Jul 2023

Scientists Use Synthetic Biology to Develop Underwater Adhesives

For more than half a century, scientists have been studying mussel foot proteins and how to synthetically duplicate their natural strength.

11 Jul 2023

Negative Modulation of Arabidopsis Salinity Tolerance by CONSTANS Protein

Arabidopsis (Arabidopsis thaliana)’s photoperiodically controlled flowering and circadian pathways are primarily regulated by CONSTANS (CO), a well-known B-box family member.

5 Jul 2023

Understanding How Malaria Parasite Modulates Apicoplast Gene Expression

A recent study supported by Tokyo Tech’s World Research Hub Initiative discovered that gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is controlled by melatonin (the circadian signaling hormone) in host blood and intrinsic parasite cues via a factor called ApSigma.

5 Jul 2023

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023

New View of Euchromatin in the Cell Analyzed

In their study performed, the research group discusses their novel view of euchromatin present in the cell and displays how the disclosed organization is appropriate to genome functions.

28 Jun 2023

Cell Fate Conversion Plays Crucial Role in Cancer Research

Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”

28 Jun 2023

Probiotic Bacteria may Help Maintain Brain Function in Aging Nematodes

A group from Nagoya University in Japan has discovered that when the diet of nematodes, tiny worms measuring about a millimeter or less in length, includes the bacteria Lactobacillus reuteri, the weakening of associative learning ability caused by aging does not occur.

28 Jun 2023

Analyzing the Cis-Regulatory Elements and Transcription Factors Related to Auxin Signaling

Phytohormones are chemical messengers that control the growth of plants and also their response to the environment.

27 Jun 2023

Using Pressure to Understand RNA Dynamics

Similar to how there are limitless secrets in space, there is still a lot to discover when looking at biomolecules, which are one trillion times smaller than a meter.

23 Jun 2023

New Approach to Revolutionize Synthetic Biology

For the first time, scientists at the Lawrence Berkeley National Laboratory of the Department of Energy (Berkeley Lab) have created a genome-scale method to map the regulatory role of transcription factors, proteins that are essential for controlling gene expression, and a plant’s physiological features.

22 Jun 2023

cBAF Protein Complex Controls the Fate of T Cells

The immune system protects the body from intruders, like bacteria, viruses, or tumors, with its intricate network of proteins, cells, and organs. Cytotoxic T cells are specialized immune cells that can grow into short-lived effector cells that destroy infected or malignant cells in human bodies.

14 Jun 2023