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New Tool Predicts How Proteins Interact with RNA Structures

Scientists at the Italian Institute of Technology and Aarhus University have figured out how specific proteins can bind to G-quadruplexes, which are unique RNA structures.

4 Apr 2024

The Influence of sRNA on Gut Pathogen Drug Susceptibility

A significant breakthrough in understanding how gut bacteria adapt to their environment.

26 Mar 2024

Researchers Unveil Simple Trick to Improve Accuracy Of Plant Genetics Research

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables – such as temperature – affect gene activity in plants.

14 Mar 2024

The Evolution of Plant Cell Analysis with RevGel-seq Technique

Plant cell analysis has been completely transformed by recent advances in single-cell RNA sequencing (scRNA), such as the recently created “RevGel-seq” technique.

13 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

13 Mar 2024

Small Genetic Element Identified as Key to Potato Industry's Production Problem

Researchers have discovered a game changer for the potato industry.

12 Mar 2024

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations.

29 Feb 2024

Retrotransposon-Based PRINT Technique Holds Potential for Precise Gene Insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

22 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

Scientists Predict DNA Mutations Causing Extra Fingers, Hearts

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

7 Feb 2024

New Insights Into How Genetic Variation Affects Gene Expression

Chromatin accessibility and transcription factor binding are determined by genetic variation, according to a recent study from the University of Eastern Finland.

23 Jan 2024

Genomic Insights Into the Evolution of Gigantism in Cetaceans

Certain gene regions in cetaceans (whales, porpoises, and dolphins) play a role in explaining the remarkable size differences among species, such as the Blue whale (Balaenoptera musculus), which can reach lengths of up to 30 m – almost 10 m longer than a bus – in contrast to the Bottlenose dolphin (Tursiops truncatus), which typically reaches a maximum length of 4 m.

23 Jan 2024

Study Uncovers Chromatin Modifier-Centered Pathway for Grain Size Regulation in Rice

Chromatin is the complex of DNA and proteins that makes up the genetic material in the nucleus of eukaryotic cells.

18 Jan 2024

The Crucial Role of Nucleolus Organizing Regions in Chestnut Genetics

The nucleolus organizing region (NOR), a crucial area of the genome, indicates that the chromosomes of Chinese and American chestnuts are not as comparable as previously thought.

16 Jan 2024

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

Spatial transcriptomics (ST) technologies are applied in biology and medical research for its ability to detect the spatial distribution of transcriptome in histological tissue slices.

3 Jan 2024

The Foundation of Gene Expression in Brain Development

Researchers from Osaka University and Shenzhen Bay Laboratory have uncovered the actions of proteins connected to memory and learning in human brain cells in a study that was just published in Cell Reports.

29 Dec 2023

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

Structural Insights Unmask Novel Adaptations and Functions of Human LINE-1 ORF2

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

20 Dec 2023

Decoding Zebrafish Development: A Comprehensive Gene Expression Atlas

Scientists from the National Institutes of Health have released a comprehensive guide to the development of zebrafish, outlining the gene expression patterns activated in almost every cell type during the initial five days of growth.

19 Dec 2023