CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Review: Role of Alternative Splicing Defects in Major Neurodegenerative Diseases

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -; single-stranded RNAs involved in protein synthesis -; and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Utilizing Genome Editing to Encourage High Crop Yields

According to a recent study released in the journal Nature on June 14th, 2023, scientists from the University of California, Davis, and an international team of researchers utilized the genome-editing tool CRISPR-Cas to generate disease-resistant rice plants.

16 Jun 2023

Dual CRISPR Gene Drive Systems Target a Specific Gene

According to recent research from North Carolina State University, scientists have created a “homing gene drive system” based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies—so-called “spotted-wing Drosophila” that severely damage soft-skinned fruit in North America, Europe, and parts of South America.

13 Jun 2023

CRISPR/Cas9 Unlocks the Key Gene in the Development of Coral Skeleton Formation

Recent research conducted by Phillip Cleves of Carnegie employs sophisticated CRISPR/Cas9 genome editing technologies to identify a gene essential to stony corals’ capacity to construct complex reef designs. Proceedings of the National Academy of Sciences published this.

6 Jun 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

1 Jun 2023

Promising Gene Editing Tool Could Tackle Antimicrobial Resistance

A new instrument that has the potential to help minimize the spread of antimicrobial resistance is revealing early potential, by using a bacterial immune system as a gene-editing tool.

26 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Novel Gene-Editing Strategy Harnesses Unusual Protective Ability to Eliminate HIV-1 Infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

22 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Researchers have developed a chicken egg that may be safe for people with egg white allergies. Chicken egg allergies are one of the most common allergies in children.

18 May 2023

Study Demonstrates the First Molecular Link Between Circatidal and Circadian Clocks

Scientists at UMass Chan Medical School and the Marine Biological Laboratory at Woods Hole have identified the first gene-; Bmal1-; to play a crucial role in regulating circatidal behavior in the crustacean Parhyale hawaiensis.

12 May 2023

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.

12 May 2023

CRISPR News and Research

Further Reading

Review: Role of Alternative Splicing Defects in Major Neurodegenerative Diseases

Utilizing Genome Editing to Encourage High Crop Yields

Dual CRISPR Gene Drive Systems Target a Specific Gene

CRISPR/Cas9 Unlocks the Key Gene in the Development of Coral Skeleton Formation

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

Promising Gene Editing Tool Could Tackle Antimicrobial Resistance

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

Novel Gene-Editing Strategy Harnesses Unusual Protective Ability to Eliminate HIV-1 Infection

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Study Demonstrates the First Molecular Link Between Circatidal and Circadian Clocks

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

Using Mass-Spectrometry-Based Cancer Proteomics Datasets to Discover Potential Therapeutic Targets

Researchers Reveal the Initiation and Early Stages of Tube Formation in the Sea Star

Scientists Engineer the First CRISPR-Based Drug Candidate to Directly Target E. Coli

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

Innate Tumor Suppression Mechanism Uncovered

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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