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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

High-Resolution Spatial Transcriptomics at Lower Cost

A novel spatial transcriptomics method that could revolutionize tissue sample gene expression profiling.

7 Aug 2024

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

In an examination of the genetic material found in historic potato leaves, North Carolina State University researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

6 Aug 2024

Unveiling the Roots of Deadly Infant Leukemia

Researchers at the Josep Carreras Leukaemia Research Institute have identified the genetic foundation for newborn B-cell Acute Lymphoblastic Leukaemia (B-ALL) glucocorticoid resistance through MLL gene rearrangements.

6 Aug 2024

Mast Cells Recruit Neutrophils in Immune Response

Mast cells are well-known for their part in allergic reactions, but the immune system relies heavily on them. They release chemicals in response to allergens, which cause common allergy symptoms like tissue swelling and inflammation.

5 Aug 2024

Shared Mechanisms in Human and Yeast DNA Replication Revealed

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.

5 Aug 2024

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

2 Aug 2024

Highly Reactive RNA Building Blocks for Enhanced Chip Production

A multinational research team under the direction of the University of Vienna has been successful in creating new RNA building blocks that exhibit increased photosensitivity and chemical reactivity. In biotechnological and medical research, RNA chips can be produced much faster as a result of this.

1 Aug 2024

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

The rapid detection of Mycobacterium tuberculosis, the etiological agent of tuberculosis.

1 Aug 2024

ETH Zurich Researchers Accelerate Bacterial Evolution for Enhanced Cellulose Production

Bacteria produce materials that are of interest to humans, such as cellulose, silk and minerals. The advantage of producing bacteria in this way is that it is sustainable, takes place at room temperature and in water.

1 Aug 2024

Biotium Releases New High-Performance Magnetic Bead-Based FFPE DNA and RNA Extraction Kits Well-Suited for Automated Processes

Biotium, a leading supplier and inventor of fluorescent probes and other novel reagents for life science research, proudly announces the availability of high-throughput compatible magnetic-bead based versions of the CELLDATA DNAstorm™ and RNAstorm™ 2.0 FFPE Extraction Kits. Following the successful 2022 acquisition and integration of Cell Data Sciences' RNAstorm™ and DNAstorm™ kits, Biotium has enhanced these kits to streamline extraction of DNA or RNA from formalin-fixed, paraffin-embedded (FFPE) tissue samples.

From Biotium, Inc. 31 Jul 2024

Transposable Elements Influence Genome Size and Gene Expression in Rosaceae Plants

Transposable elements are mobile DNA sequences that play a crucial role in plant genome architecture and gene regulation.

30 Jul 2024

New Study Uncovers Genetic Secrets of Cotton's Drought Resilience

Cotton is woven into the very fabric of our lives, from soft T-shirts to comfortable jeans and cozy bedsheets.

30 Jul 2024

CRISPR-Cas Vs. Anti-CRISPR Proteins: The Battle Over Antibiotic Resistance In Bacteria

The relationship between antibiotic resistance in bacteria and the interactions between the CRISPR-Cas system and anti-CRISPR proteins.

30 Jul 2024

Study Reveals Widespread Gene Misbehavior in Healthy Humans

Scientists have uncovered that ‘gene misbehaviour’ – where genes are active when they were expected to be switched off – is a surprisingly common phenomenon in the healthy human population.

29 Jul 2024

Scientists Find Way to Regulate Bacterial Mutation Rates to Combat Antibiotic Resistance

Scientists have discovered a way to control mutation rates in bacteria, paving the way for new strategies to combat antibiotic resistance.

29 Jul 2024

Researchers Discover Link Between Neolithic Farming and Brucellosis

Scientists believe the bacterial infection brucellosis, which affects millions of people every year and causes significant harm to the welfare of livestock, may have evolved along with the development of farming. They came to this conclusion after performing analyses of ancient DNA extracted from an 8,000-year-old sheep bone, in which the Brucella melitensis pathogen was detected.

29 Jul 2024

Effective Plasmid DNA Delivery Achieved with Zwitterionic Polymer Complex

Researchers from Tokyo Metropolitan University have created a new drug delivering molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RNA and proteins. The new compound effectively bound to plasmid DNA without affecting its structure. Injected into mouse muscles, the team observed widespread gene expression, promising applications to treatments of serious muscle diseases.

29 Jul 2024

Plant-Based Diet Slows Down Biological Aging Markers

Eating a vegan diet for eight weeks is associated with reductions in biological age estimations based on levels of DNA methylation -; a type of chemical modification of DNA (known as an epigenetic modification) that alters gene expression but not DNA itself. Previous research has reported that increased DNA methylation levels are associated with aging. The findings, which are based on a small randomized controlled trial of 21 pairs of adult identical twins, are published in BMC Medicine.

29 Jul 2024

Unraveling the Complexities of X Chromosome Inheritance

A new study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences has reveals that the contribution of cells expressing maternal or paternal X chromosomes can be selectively skewed in different parts of the body.

26 Jul 2024

Cost-Effective Array Sheds Light on Imprinted Gene Regulation

Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array represents a cost-effective, efficient method for exploring potential links between environmental exposures and epigenetic dysregulation during the early developmental origins of diseases and behavioral disorders.

26 Jul 2024

DNA News and Research

Further Reading

High-Resolution Spatial Transcriptomics at Lower Cost

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

Unveiling the Roots of Deadly Infant Leukemia

Mast Cells Recruit Neutrophils in Immune Response

Shared Mechanisms in Human and Yeast DNA Replication Revealed

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Highly Reactive RNA Building Blocks for Enhanced Chip Production

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

ETH Zurich Researchers Accelerate Bacterial Evolution for Enhanced Cellulose Production

Biotium Releases New High-Performance Magnetic Bead-Based FFPE DNA and RNA Extraction Kits Well-Suited for Automated Processes

Transposable Elements Influence Genome Size and Gene Expression in Rosaceae Plants

New Study Uncovers Genetic Secrets of Cotton's Drought Resilience

CRISPR-Cas Vs. Anti-CRISPR Proteins: The Battle Over Antibiotic Resistance In Bacteria

Study Reveals Widespread Gene Misbehavior in Healthy Humans

Scientists Find Way to Regulate Bacterial Mutation Rates to Combat Antibiotic Resistance

Researchers Discover Link Between Neolithic Farming and Brucellosis

Effective Plasmid DNA Delivery Achieved with Zwitterionic Polymer Complex

Plant-Based Diet Slows Down Biological Aging Markers

Unraveling the Complexities of X Chromosome Inheritance

Cost-Effective Array Sheds Light on Imprinted Gene Regulation

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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