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Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

The University of Texas MD Anderson Cancer Center scientists have created an ultrasound-guided cancer immunotherapy approach that promotes systemic antitumor immunity and increases immune checkpoint blockade therapeutic potential. Nature Nanotechnology published the results of the pioneering study.

1 Jun 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

A preclinical study performed by Monash University researchers discovered that utilizing a combination of phages and antibiotics to treat bacterial infections may be considerably more successful than using the drugs separately.

12 May 2022

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators.

22 Apr 2022

Researchers create RNA molecules to address human pancreatic beta cells

Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.

11 Apr 2022

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet.

25 Mar 2022

Gene mutation influences autism development, study finds

A research team discovered that interruption of a circadian clock gene may be implicated in the formation of autism spectrum disorder.

25 Mar 2022

Experts investigate the activity of genes in dog brain tissues

Upon examining the gene activity in dog brain tissues, it was revealed that a major part is active in every animal.

23 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

Newly developed radio-labeled molecule may be able to pinpoint areas of inflammation

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

22 Feb 2022

Fungi residing in the intestines protect against intestinal injury, study finds

According to a recent preclinical study from Weill Cornell Medicine, a certain species of fungus found in the intestines can protect against intestinal damage.

22 Feb 2022

CNIO researchers design new platform to test drugs for possible use in brain metastases

It is estimated that about a quarter of cancer patients are at risk of brain metastases, a rate that is increasing especially among those who suffer relapses after having undergone different cancer treatments.

18 Feb 2022

Researchers discover dysregulation of transfer RNA expression in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

Preclinical News and Research

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

Researchers devise a new treatment approach to cure aggressive brain tumors

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Researchers create RNA molecules to address human pancreatic beta cells

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Gene mutation influences autism development, study finds

Experts investigate the activity of genes in dog brain tissues

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Newly developed radio-labeled molecule may be able to pinpoint areas of inflammation

Fungi residing in the intestines protect against intestinal injury, study finds

CNIO researchers design new platform to test drugs for possible use in brain metastases

Researchers discover dysregulation of transfer RNA expression in cancer

Study shows how the commensal oral microbiome can regulate alveolar bone health

Human nose organoids reveal the first events of SARS-CoV-2 and RSV infection

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Research highlights how carnosic acid found in rosemary inhibits SARS-CoV-2 infection

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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