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Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

The Omicron variant was detected for the first time in South Africa in November 2021 and has since spread to many countries.

From Institut Pasteur 10 Jan 2022

CAR T cells produced in vivo using modified mRNA treat cardiac injury

A new study by researchers from the University of Pennsylvania shows that experimental immunotherapy can temporarily reprogram the immune cells of patients.

10 Jan 2022

Research provides novel insights on cancer immunotherapy

UC San Francisco researchers have defined 12 classes of “immune archetypes” to identify cancer tumors based on data from over 300 patient tumors.

10 Jan 2022

Cryo-ET reveals mechanisms underlying gene mutations that lead to blindness

Researchers have discovered the structural determinants of the highly specialized rod outer segments membrane architecture of the eye, which plays a crucial role in vision.

7 Jan 2022

Research shows how bacteria silence potentially deadly genes

Humans are all made of collections of cells, where each cell contains instructions in the DNA to become another cell.

7 Jan 2022

Experts introduce new gene therapy approach for muscle weakness

Experts at Children’s National Hospital have created a new pre-clinical gene therapy for the rare condition limb-girdle muscular dystrophy (LGMD) 2B.

7 Jan 2022

Superbug MRSA emerged in hedgehogs long before the use of antibiotics in humans

Scientists have found evidence that a type of the antibiotic resistant superbug MRSA arose in nature long before the use of antibiotics in humans and livestock, which has traditionally been blamed for its emergence.

6 Jan 2022

A folic acid-like drug changes a DNA process within brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

From Vanderbilt University 6 Jan 2022

New model system reveals how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

4 Jan 2022

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Researchers at the University of Illinois Chicago have designed a high-quality assay that can be used in at-home tests for rapid COVID-19 screening.

4 Jan 2022

Researchers develop new CAR T cells that act as a "micropharmacy"

Immunotherapies called chimeric antigen receptor (CAR) T cells use genetically engineered versions of a patient's own immune cells to fight cancer. These treatments have energized cancer care, especially for people with certain types of blood cancers.

3 Jan 2022

Research highlights opportunities to expand the manufacture of stem cells in space

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

3 Jan 2022

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

A new technique takes bioprinting -; in which an ink of cells is printed, layer by layer, to form a structure -; to a whole new, and icy level. Investigators from the Zhang lab at Brigham and Women's Hospital have developed a technology that they term "cryobioprinting," a method that uses a bioink embedded with cells to print frozen, complex structures that can be easily stored for later use.

31 Dec 2021

Genes key to microbial colonization of plant roots discovered

Some microbes can form thin films called biofilms. These biofilms give them an advantage over other microbes by protecting them from stresses such as a lack of nutrients or the presence of harmful substances in the environment.

24 Dec 2021

COVID-19 virus spreads through cell-to-cell transmission

The virus that causes COVID-19 has adopted some stealth moves to stay alive and kicking, and one secret to its success is hiding from the immune system by spreading through cell-to-cell transmission, a new study has found.

24 Dec 2021

Unraveling how DNAzymes work in real time

DNAzymes are precision biocatalysts that destroy unwanted RNA molecules. However, major obstacles to their use in medicine remain.

23 Dec 2021

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

Experts carry out the first major genetic study into cortical folding patterns

The brain’s surface, the cortex, is folded into an intricate pattern of grooves (sulci) and bumps (gyri). Individual differences in this pattern are associated with cognitive performance and brain disorders, however very little is known on how the “bumpiness and grooviness” of the cortex is determined.

23 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021

Medicine News and Research

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

CAR T cells produced in vivo using modified mRNA treat cardiac injury

Research provides novel insights on cancer immunotherapy

Cryo-ET reveals mechanisms underlying gene mutations that lead to blindness

Research shows how bacteria silence potentially deadly genes

Experts introduce new gene therapy approach for muscle weakness

Superbug MRSA emerged in hedgehogs long before the use of antibiotics in humans

A folic acid-like drug changes a DNA process within brain tumors

New model system reveals how tiny bacteria from the environment have adapted to live inside humans

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Researchers develop new CAR T cells that act as a "micropharmacy"

Research highlights opportunities to expand the manufacture of stem cells in space

Cryobioprinting uses a bioink embedded with cells to print frozen and complex structures

Genes key to microbial colonization of plant roots discovered

COVID-19 virus spreads through cell-to-cell transmission

Unraveling how DNAzymes work in real time

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Experts carry out the first major genetic study into cortical folding patterns

Study identifies novel function for existing protein

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