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Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting more than 10 million people worldwide and more than one million Americans. While there is no cure for PD, current therapies focus on treating motor symptoms and fail to reverse, or even address, the underlying neurological damage.

26 Oct 2021

New insight into how neurons and astrocytes work together to form healthy synapses

Brain cells called astrocytes play a key role in helping neurons develop and function properly, but there's still a lot scientists don't understand about how astrocytes perform these important jobs.

26 Oct 2021

Scientists identify genes responsible for allowing Candida fungus to survive treatment

It is estimated that 80% of women will suffer from vaginal candidiasis at least once in their lives. In addition to superficial infections, which can be oral or vaginal and do not usually have a serious prognosis, fungi of the Candida genus can cause systemic diseases in immunocompromised individuals and these are fatal in 40% of cases.

26 Oct 2021

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.

26 Oct 2021

Research opens new therapeutic perspectives for treatment of skin fibrosis

Collagen, the main component of the skin's extracellular matrix, can cause a pathological condition if it is in excess. Applying an electric field to the skin affects collagen pathways, temporarily reducing collagen production and increasing its degradation.

22 Oct 2021

Enteric glial cells play a major role in gut immunity, says new study

Scientists from the Francis Crick Institute unraveled a basic role of glial cells in the nervous system of the gut in retaining a healthy intestine.

22 Oct 2021

Study pinpoints the mutational hotspots in DNA

Recent research at the University of Bath reveals that tangles in unwound DNA can develop mutational hotspots in the genomes of bacteria.

From University of Bath 21 Oct 2021

Mitochondria of diabetic patients can't keep track of time, study finds

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night.

21 Oct 2021

Researchers reveal how bacteria make liquid protein droplets to survive harsh environments

Scientists have revealed how bacteria make tiny liquid droplets from proteins to help them survive harsh environments and thus reduce their chances of being killed by antibiotics.

21 Oct 2021

Our genes may be an unexpected contributor to pro-conservation sentiment

As global environmental crises mount, numerous policies have been proposed with an eye toward a more sustainable future. However, such recommendations have often gone unheeded, falling by the wayside for lack of public support.

21 Oct 2021

Study investigates the role of essential genes in acetic acid tolerance

Saccharomyces cerevisiae, also known as Baker’s yeast, is industrially utilized for the production of different biochemicals.

21 Oct 2021

Experts explain left–right asymmetry development in the embryo

Research on the development of symmetry in mice embryos is anticipated to provide a deeper understanding of the causes of disease.

21 Oct 2021

'Switching on' Sight using Gene Therapy

AZoLifeSciences speaks to Dr. Raymond Wong about his latest research into eye health and we could potentially 'switch on' sight using gene therapy.

20 Oct 2021

Study uncovers new gene variants that may cause inherited retinal dystrophies

An international team of researchers, led by scientists at University of California San Diego and Shiley Eye Institute at UC San Diego Health, has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.

20 Oct 2021

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Study finds novel genes linked to fibromuscular dysplasia using genetic meta-analysis

Recent research identified that three novel genetic variants that control gene expression in the arteries are linked to fibromuscular dysplasia (FMD)—an arterial disease that induces threatening impacts for the heart and vessels.

19 Oct 2021

Disease genes are unable to adapt as the rest of the genome, says research

Researchers recently discovered a novel detrimental effect of genes that induce inherited diseases. The observations are published in the journal eLife.

19 Oct 2021

Researchers identify the best responding odorant receptors for furaneol

The aroma of caramel is liked by most, but to date, the olfactory receptor that contributes decisively to this sensory impression was not known.

19 Oct 2021

Researchers map proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, challenging the categorisation of diseases by organ, symptoms, or clinical speciality.

18 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Genes News and Research

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

New insight into how neurons and astrocytes work together to form healthy synapses

Scientists identify genes responsible for allowing Candida fungus to survive treatment

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

Research opens new therapeutic perspectives for treatment of skin fibrosis

Enteric glial cells play a major role in gut immunity, says new study

Study pinpoints the mutational hotspots in DNA

Mitochondria of diabetic patients can't keep track of time, study finds

Researchers reveal how bacteria make liquid protein droplets to survive harsh environments

Our genes may be an unexpected contributor to pro-conservation sentiment

Study investigates the role of essential genes in acetic acid tolerance

Experts explain left–right asymmetry development in the embryo

'Switching on' Sight using Gene Therapy

Study uncovers new gene variants that may cause inherited retinal dystrophies

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Study finds novel genes linked to fibromuscular dysplasia using genetic meta-analysis

Disease genes are unable to adapt as the rest of the genome, says research

Researchers identify the best responding odorant receptors for furaneol

Researchers map proteo-genomic connections between different human diseases

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

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