ACE Inhibitors News and Research

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ACE inhibitors act to reduce hypertension by interfering with the conversion of angiotensin I to artery-constricting angiotensin II. Blocking the production of angiotensin II results in arterial vasodilation and an accompanying reduction in blood pressure. ACE inhibitors currently are recommended as first-line therapy for hypertension in certain patient populations, because of their safety and efficacy.

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

University of Cape Town (UCT) researchers have used cryo-electron microscopy to identify the first complete structures of the human angiotensin-converting enzyme (ACE) (cryo-EM). A protein that controls blood pressure, ACE, is essential for maintaining good heart health.

14 Jul 2022

Gut microbiota may play a role in resistance to blood pressure medicines

Gut microbiota may play a role in resistance to blood pressure medicines

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

6 Apr 2022

Augmented response of immune system explains COVID-19 severity in patients with hypertension

Augmented response of immune system explains COVID-19 severity in patients with hypertension

COVID-19 patients who also suffer from high blood pressure are more likely to fall severely ill with the disease, which also leaves them at greater risk of death.

12 Jan 2021

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

Nearly 20% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community.

15 Jul 2020

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

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