Angiogenesis News and Research

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Angiogenesis is blood vessel formation. Tumor angiogenesis is the growth of new blood vessels that tumors need to grow. This is caused by the release of chemicals by the tumor.

From Bone Regeneration to Heart Repair: Stem Cell Transplantation Paves the Way for New Medical Frontiers

Stem cell transplantation offers promising solutions for tissue regeneration and age-related degeneration, despite challenges in safety and production costs.

9 Sep 2024

Inverse relationship found between anti-inflammatory macrophages and NK cells/T cells in lung cancer

Single-cell ribonucleic acid sequencing (scRNAseq) and spatial transcriptomics to study cellular organization and interactions within the tumor microenvironment.

30 May 2024

UNC Researchers Create Key Tool for Kaposi Sarcoma Drug Development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

30 Apr 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

5 Jan 2024

DiNP Exposure in Early Pregnancy May Cause Birth Defects

We are constantly exposed to phthalates in our environment through plastic products such as storage containers, medical devices, packages, fabrics, and toys. Specifically, di-isononyl phthalate is inevitably becoming a part of our lives. Unfortunately, the impact of DiNP on the establishment and maintenance of pregnancy is largely unknown. In a new study, researchers used mice to understand how DiNP affects pregnancy.

4 Sep 2023

Endothelial Deletion of Wt1 Gene During Coronary Vessel Formation Affects Embryonic Heart Development

How is the mammals' heart formed? What role do endothelial cells play? Do the same pathways and genes involved in the formation of the embryonic heart also play a role in repair processes?

4 Apr 2023

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

30 Jan 2023

Researchers discover a significant health food ingredient

Aggrecan, a significant component of proteoglycan (PG) in cartilaginous tissues with chondroitin sulfate (CS), is becoming more popular as a wellness food ingredient.

From Tokyo University of Science 30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Bone growth protein may help treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

22 Apr 2022

Curcumin released from magnetic hydrogels can aid in vascular regeneration

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients.

7 Apr 2022

Powerhouse-pruning protein may be a sound target to help trigger new blood vessel growth

A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.

5 Apr 2022

Phenolic extract from blueberries enhance vascularization and cell migration

According to a new study, treating wounds with an extract made from wild blueberries can help them recover faster. The findings will be presented at the American Physiological Society’s (APS) annual meeting, Experimental Biology 2022, in Philadelphia.

5 Apr 2022

Unusual partners aid new blood vessel development

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

9 Mar 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Intussusceptive angiogenesis contributes to growth of daughter tumors in malignant melanoma

For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of new blood vessel branches, but also an alternative process in which one blood vessel divide into two parallel vessels bylongitudinal splitting.

28 Oct 2021

Common drug to treat cancer reverses Alzheimer’s symptoms in mice

A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.

6 Oct 2021

New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

Newly designed higher affinity monoclonal antibody for cancer treatment

Recently, Prof. XIE Can from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science (HFIPS), in a collaboration with Prof. YAN Xiyun's lab from the Institute of Biophysics, reported the structural basis of mAb AA98's inhibition on CD146-mediated endothelial cells (EC) activation and designed higher affinity monoclonal antibody HA98 for cancer treatment.

10 May 2021