Cell Metabolism News and Research

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Gut Bacteria Influence Stress Responses Through Circadian Rhythms

A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with the body's circadian rhythms.

6 Nov 2024

Unveiling the Link Between Genetics, Stress, and Type 2 Diabetes

The cells in the human pancreas have a limit to how much stress they can withstand before degenerating.

10 Oct 2024

A New Understanding of the Effects of Fever on Immune Cells

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also -; in a particular subset of T cells -; cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

23 Sep 2024

New AI Tool Deciphers Cellular Metabolism

Biology depends on humans' ability to comprehend metabolism, the process by which cells use resources and create energy.

2 Sep 2024

Arctic Actinobacteria Yield Novel Antivirulence Compounds Against E. coli

A novel set of techniques was created by researchers in Finland and Norway to screen unknown substances with bacterial origin for antivirulence activity.

2 Sep 2024

New Screening Methods Uncover Antivirulence Compounds from Arctic Actinobacteria

Antibiotics are the linchpin of modern medicine: without them, anyone with open wounds or needing to undergo surgery would be at constant risk of dangerous infections.

27 Aug 2024

New Discovery in Mitochondrial DNA Regulation May Halt Heritable Disease Onset

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

23 Aug 2024

New Tool GeneMAP Unveils Key Insights into Cell Metabolism

There's a glaring gap in our knowledge of cell metabolism: in many cases, we still don't know exactly how nutrients are transported into the cell.

24 Jul 2024

Breakthrough Study Reveals How Toxoplasma gondii Alters Host Cell Metabolism

Toxoplasma gondii is a parasite responsible for toxoplasmosis, a lifelong chronic infection prevalent in about 30% of the human population.

12 Jul 2024

Study Highlights Key Protein-Lipid Interactions in Mitochondrial Energy Production

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

10 Jun 2024

Glutamate tRNA Fragments Play Key Role in Brain Aging and Alzheimer's Disease

A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease.

14 May 2024

Unraveling the Molecular Landscape of Parietal Cell Development

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal activity of parietal cells (PCs) in the stomach, the only cells in the body that produce acid.

13 May 2024

New Population of Cells in Human Omental Fat Tissue Found to Hinder Adipogenesis

Understanding how fat tissue forms and functions is crucial for addressing obesity and related metabolic diseases. However, adipose tissue, or body fat, behaves differently based on its location in the body.

10 May 2024

Using State-of-the Art Imaging to Understand Lipid Dysfunction in Alzheimer's

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

24 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

New Theory Links Gene Length to Cellular Decline

A gene’s length may have more to do with aging than particular “aging genes.” Reduced expression of long genes may be the cause of many aging-related changes, according to researchers writing an opinion piece that was published in the journal Trends in Genetics on March 21st, 2023.

25 Mar 2024

Unraveling the Role of Gene Length in Aging

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024

Gut Microbial Metabolite Linked to Increased Thrombosis Risk in COVID-19 Patients

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

26 Feb 2024