Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

Cryo-EM Uncovers Hidden Complexity in Collagen Structure

The most prevalent protein in the body, collagen, has long been thought to be a predictable structural element of tissues.

10 Feb 2025

Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology, transforming protein engineering.

3 Feb 2025

Temperature-Sensitive Protein Enables Non-Invasive Control of Cellular Behavior

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

30 Jan 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

Coordinated Behavior in Choanoflagellates Provides Evolutionary Clues

A new study published in Science Advances reveals evidence of electrical signaling and coordinated behavior in choanoflagellates, the closest living relatives of animals.

9 Jan 2025

New Mechanism Revealed for Immune Response to DNA Damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

7 Jan 2025

New Method Improves Quantification of Endocytosis in Living Cells

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment.

23 Dec 2024

SMART Software Unlocks New Insights into Cellular Dynamics

Researchers at University of California San Diego have developed and tested a new software package, called Spatial Modeling Algorithms for Reactions and Transport (SMART), that can realistically simulate cell-signaling networks -; the complex systems of molecular interactions that allow cells to respond to diverse cues from their environment.

20 Dec 2024

New Discovery Redefines the Shape of Axons in Mammalian Brain Cells

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

3 Dec 2024

Reduced Protein Mobility Linked to Chronic Diseases and Their Complications

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

28 Nov 2024

MicroQuin's Space Research Paves Way for Potential Cancer Treatment

In October, we think pink, and for a good reason—one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis.

4 Nov 2024

New Insights into the Mechanism of Glycan Branch Formation

Glycans are sugar chains that bind to cells via proteins or lipids, altering their chemical properties

30 Oct 2024

Novel Mechanism for GRB2-SOS1-Mediated Liquid-Liquid Phase Separation

Researchers at Tokyo Metropolitan University have discovered new details about how the proteins GRB2 and SOS1 in cells transmit signals from membrane receptors to nuclei.

28 Oct 2024

Unveiling the Potential of YY1 in Blood Cell Development and Therapy

Common lymphoid progenitors, pre-pro-B cells, pro-B cells, pre-B cells, immature B cells, and finally more mature and specialized B cells are the stages in which B cells, white blood cells that produce antibodies, develop.

17 Oct 2024

Disrupting a Gene Boosts T Cell Therapy, St. Jude Study Shows

Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most.

15 Oct 2024

Unveiling the Protective Role of KLF6 in Diabetic Kidney Disease

Research by Stony Brook Medicine nephrology specialists may help prevent or reduce diabetic kidney disease progression by targeting cellular signaling between kidney cells and inducing a specific gene.

11 Oct 2024

Lipids Found to Play Key Role in Cancer Immune Evasion

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes.

18 Sep 2024

The Molecular Process That Causes MS and Autoimmune Diseases

A human immune system suppressor known as “regulatory T cells” was first identified more than 20 years ago by a research team working in the lab of Yale researcher David Hafler, who was at Harvard at the time.

29 Aug 2024

ENGRAM: Capturing Cellular Histories Through Genomic Recording

Genomes can now be entrusted to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft.

18 Jul 2024