Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 14, one copy inherited from each parent, form one of the pairs. Chromosome 14 spans about 106 million DNA building blocks (base pairs) and represents 3 percent to 3.5 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 14 likely contains between 800 and 1,300 genes.
Genes on chromosome 14 are among the estimated 20,000 to 25,000 total genes in the human genome.
A lot of biological mechanisms go wrong in cancer—for example genes mutate and cells proliferate in an uncontrollable manner.
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