Cytometry News and Research

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How B Cells Know When to Mutate—and When to Chill

Study reveals B cells suppress mutations during rapid division, enhancing immune response and offering critical insights for vaccine and treatment development.

27 Mar 2025

New Insights into How B Cells Strategically Clone High-Affinity Antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

20 Mar 2025

$30 Million Grant Supports AI-Powered Antibody Therapy Development

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

10 Mar 2025

New AI-Based Device Makes Flow Cytometry Affordable and Accessible

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry ⎯ a technique used to analyze cells or particles in a fluid using a laser beam ⎯ affordable and accessible.

3 Mar 2025

RNA Splicing Errors May Hold the Key to Beating Gliomas Using Immunotherapy

Identifying splicing-related neoantigens in gliomas opens new avenues for immunotherapy, enhancing treatment strategies for this challenging brain tumor.

26 Feb 2025

Zika Virus Hijacks Placental Tunnels to Evade Immune Defense

Infection with Zika virus in pregnancy can lead to neurological disorders, fetal abnormalities and fetal death. Until now, how the virus manages to cross the placenta, which nurtures the developing fetus and forms a strong barrier against microbes and chemicals that could harm the fetus, has not been clear.

24 Feb 2025

New CRISPR Tool Reveals Key Lymphoma Genes

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

7 Feb 2025

CryoSCAPE Enables Accurate Single-Cell Profiling in Diverse Populations

Human blood is a complex and delicate mixture, often used by researchers and clinicians to understand the body’s inner workings.

7 Jan 2025

Discovery of 18-Digit Code Unlocks Exosome-Based Drug Delivery

Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver biochemical signals.

12 Dec 2024

New Role for the Golgi Apparatus in Cancer Immunotherapy

The Golgi apparatus modifies, sorts, and packages proteins to be sent to their final destinations, whether that is within or outside of the cell.

25 Nov 2024

MIT Engineers Develop Model to Decode Complex Biological Systems

Over the past two decades, new technologies have helped scientists generate a vast amount of biological data. Large-scale experiments in genomics, transcriptomics, proteomics, and cytometry can produce enormous quantities of data from a given cellular or multicellular system.

6 Nov 2024

New Discovery Shows TAGLN2 Protein Boosts T Cell Immunity Against Tumors by Enhancing Lipid Metabolism

Findings indicate ovarian cancer disrupts CD8+ T cell metabolism through FABP5 and TAGLN2, suggesting new therapeutic targets for enhancing immune function.

1 Nov 2024

New Insights Into Early Brain Development and Mental Health

An unparalleled glimpse at how gene regulation changes during human brain development has been provided by a study led by UCLA, which demonstrates the crucial role played by the 3D structure of chromatin, which is made up of proteins and DNA.

10 Oct 2024

Atypical B Cells Play a Central Role in COVID-19 Vaccine Response

Vaccines function by strengthening defenses against viruses that invade human bodies. Vaccination against COVID-19 teaches the human immune system's specialized B cells how to identify the virus.

5 Sep 2024

Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Research identifies two states of age-associated thymic epithelial cells, linking thymic degeneration to aging and injury, impacting immune system function.

26 Aug 2024

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Research on intestinal immuno-organoids reveals their potential in modeling immune interactions and studying intestinal diseases linked to cancer therapies.

26 Aug 2024

Bio-Rad Launches Annexin V StarBright Conjugates for Apoptosis Detection via Flow Cytometry

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIO.B), a global leader in life science research and clinical diagnostics products, today announced the launch of annexin V conjugated to eight StarBright Dyes: SBUV400, SBUV795, SBV440, SBV515, SBV790, SBB675, SBB765, SBY800. The new Annexin V StarBright conjugates support detection of early apoptotic cells by flow cytometry, offering an increased range of fluorophore options.

9 Aug 2024

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

5 Aug 2024

Harvard Researchers Crack the Code on Western Equine Encephalitis Decline

The story of the rise and fall of western equine encephalitis as a lethal disease offers essential lessons about how a pathogen can gain or lose its ability to jump from animals to humans.

29 Jul 2024

Unveiling IRF1's Influence on Cancer Progression and Treatment Using Histology and Flow Cytometry

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have discovered new information regarding the function of a protein known as interferon regulatory factor (IRF1) in the course of cancer and how it responds to treatment. This information may help increase the efficacy of cancer immunotherapy.

16 Jul 2024