Depressive Disorder News and Research

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Key Mediator of Anhedonia-Like Behavior Identified

Researchers uncovered a stress-regulated gene that is important in the relationship between chronic stress and typical depressed behavior in mice.

10 Apr 2023

T cell-driven changes in the gut may affect brain function associated with depression

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

21 Mar 2023

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Individuals with cocaine use disorder exhibit gene expression changes in two brain regions: the nucleus accumbens, a region associated with reward, and the caudate nucleus, a region mediating habit formation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published February 10 in Science Advances.

13 Feb 2023

Trial assesses the impact of Mediterranean diet on depression symptoms in young men

Depression is a common mental health condition that affects approximately 1 million Australians each year. It is a significant risk factor for suicide, the leading cause of death in young adults.

10 May 2022

Research associates depressive diseases and deformability of blood cells

For the first time, a study conducted by the TU Dresden and the University of Zurich in collaboration with the Max Planck Institute for the Science of Light finds a relationship between depressive disorders and mechanical features of all main blood cell types.

19 Apr 2022

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

8 Mar 2022

Study discovers common genetic factors between depression and Alzheimer’s disease

Recent research discovered common genetic factors between depression and AD.

18 Feb 2022

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

The World Health Organization estimates that nearly 280 million people worldwide suffer from depression.

2 Feb 2022

Adolescents with higher omega-3 levels in blood are less likely to acquire psychotic illness

Adolescents who had greater levels of an omega-3 fatty acid in their blood were less likely to acquire psychotic illness in early adulthood.

3 Jun 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

Metabolites may be predictive indicators for recurrent major depressive disorder

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -- small molecules produced by the process of metabolism -- may be predictive indicators for persons at risk for recurrent major depressive disorder.

13 Jan 2021

Disturbances in the gut microbiome may explain major depressive disorder

Researchers have successfully detected three bacteriophages, 50 fecal metabolites, 47 bacterial species that were considerably more or less abundant in patients with major depressive disorder (MDD) when compared to healthy controls. The study involved 311 individuals.

4 Dec 2020

New findings help to better understand the genetics of neuropsychiatric disorders

A new study led by NorthShore University HealthSystem (NorthShore) and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

5 Aug 2020

Depressive Disorder News and Research

Key Mediator of Anhedonia-Like Behavior Identified

T cell-driven changes in the gut may affect brain function associated with depression

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Trial assesses the impact of Mediterranean diet on depression symptoms in young men

Research associates depressive diseases and deformability of blood cells

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

Study discovers common genetic factors between depression and Alzheimer’s disease

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

Adolescents with higher omega-3 levels in blood are less likely to acquire psychotic illness

Gender difference accounts for major psychiatric disorders

Metabolites may be predictive indicators for recurrent major depressive disorder

Disturbances in the gut microbiome may explain major depressive disorder

New findings help to better understand the genetics of neuropsychiatric disorders

Study estimates the cost-effectiveness of esketamine used for treating depression

Fish Oil May Help With Depression

Study identifies that the JNK protein is a stress sensor in synapses

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