Diarrhea News and Research

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Diarrhea is loose, watery stools. A person with diarrhea typically passes stool more than three times a day. People with diarrhea may pass more than a quart of stool a day. Acute diarrhea is a common problem that usually lasts 1 or 2 days and goes away on its own without special treatment. Prolonged diarrhea persisting for more than 2 days may be a sign of a more serious problem and poses the risk of dehydration. Chronic diarrhea may be a feature of a chronic disease.

Diarrhea can cause dehydration, which means the body lacks enough fluid to function properly. Dehydration is particularly dangerous in children and older people, and it must be treated promptly to avoid serious health problems.

Novel Cellular Atlas of the Human Gastrointestinal Tract

Spatial and single-cell data from 1.6 million cells have been combined to produce the most complete cell map of the human stomach to date.

21 Nov 2024

Unveiling the Clinical Significance of Microbial Load in Human Health

Scientists built a new machine-learning model to predict microbial load — the density of microorganisms in the guts — and used it to explain how microbial load plays an essential role in disease-microbiome relationships.

14 Nov 2024

New Research Reveals Link Between Stress Response and C. difficile Severity

The portion of our nervous systems responsible for the "fight or flight" response can shape the severity of potentially deadly C. difficile infections, new research from the University of Virginia School of Medicine reveals.

14 Oct 2024

Genome-Scale Analysis Reveals Cholera's Evolution

The genetic components that make the cholera-causing bacterium so lethal have been identified by experts using a state-of-the-art computational method, and this information may be crucial to averting the terrible illness.

24 Sep 2024

Arctic Actinobacteria Yield Novel Antivirulence Compounds Against E. coli

A novel set of techniques was created by researchers in Finland and Norway to screen unknown substances with bacterial origin for antivirulence activity.

2 Sep 2024

Gut Microbiota Modulates Rotavirus Vaccine Effectiveness

Scientists at Georgia State University's Institute for Biomedical Sciences have shown that some gut flora can reduce the effectiveness of the rotavirus vaccine.

27 Aug 2024

New Screening Methods Uncover Antivirulence Compounds from Arctic Actinobacteria

Antibiotics are the linchpin of modern medicine: without them, anyone with open wounds or needing to undergo surgery would be at constant risk of dangerous infections.

27 Aug 2024

Mini-Gut Model Unlocks Secrets of COVID-19 Diarrhea

Researchers at Johns Hopkins Medicine claim to have identified multiple molecular pathways linked to diarrhea caused by COVID-19, offering possible therapeutic interventions utilizing human stem cells to create a sort of “mini intestine-in-a-dish.

7 Aug 2024

Zebrafish Embryo Model Unveils Breakthrough Cultivation Method

Researchers at the National University of Singapore (NUS) specializing in food virology have achieved successful cultivation of the human norovirus using zebrafish embryos.

29 Dec 2023

Study Uncovers Genes in Gut Microbe That Play Key Role in Early Colonization After Fecal Microbe Transplant

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants,

16 Oct 2023

A Colonizing Strategy of Salmonella Gut Bacteria

According to researchers at ETH Zurich, when the gut is already populated by a closely similar strain of Salmonella bacteria, it only requires the capacity to use a single other food source for the bacteria to flourish.

22 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Nasal Swab Proves to Determine the Effectiveness of Antibiotics

According to a recent JAMA study by scientists at the University of Pittsburgh and UPMC, a nasal swab to screen for three types of bacteria can reveal whether or not antibiotics are likely to be beneficial in children with suspected sinusitis.

26 Jul 2023

Fecal Microbiota Transplantation to Help in Clostridioides difficile Infection

In Europe, Clostridioides difficile infection results in severe diarrhea and leads to the death of around 20,000 patients, every year. It is one of the most common hospital-acquired infections.

16 May 2023

Gut Microbiota Interspecies Interactions may Impact the Efficacy of Antibiotics Against C. Difficile

Clostridioides difficile (C. difficile) is a bacterium that can infect the large intestine, with symptoms ranging from diarrhea to life-threatening colon damage.

12 May 2023

First Gene-Edited Calf Produced With Resistance to Bovine Viral Diarrhea Virus

Scientists have collaborated to produce the first gene-edited calf with resistance to bovine viral diarrhea virus (BVDV), a virus that costs the U.S. cattle sector billions of dollars annually.

10 May 2023

How Bacteria Take Action to Break Out of Dormancy

Solving a riddle that has confounded biologists since bacterial spores -; inert, sleeping bacteria -; were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

2 May 2023

Food-Poisoning Bacteria Create Syringe-Like Structures to Inject Toxins Into Intestinal Cells

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

21 Apr 2023

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

Revealing the structural basis underpinning the biophysical properties of pili

According to the World Health Organization, enterotoxigenic Escherichia coli (ETEC) bacteria are the most common cause of traveler’s diarrhea and cause the greatest number of known community-acquired cases of childhood diarrhea in the developing world.

31 Mar 2023