Fluorescent Protein News and Research

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Scientists Build Live African Swine Fever Virus From Synthetic DNA Using CRISPR

Utilizing CRISPR-Cas9, scientists reconstitute live African swine fever virus from synthetic genomes, accelerating vaccine development for this deadly virus.

2 Apr 2025

Enhanced Embryo Screening Efficiency in Primate Genetic Modification

Genetic engineering in non-human primates has historically faced limitations due to the reliance on virus-based gene delivery methods.

26 Mar 2025

Researchers Capture Breakthrough Images of Cellulose Synthesis in Living Plant Cells

In a groundbreaking study on the synthesis of cellulose – a major constituent of all plant cell walls – a team of Rutgers University-New Brunswick researchers has captured images of the microscopic process of cell-wall building continuously over 24 hours with living plant cells, providing critical insights that may lead to the development of more robust plants for increased food and lower-cost biofuels production.

24 Mar 2025

CRISPR Unlocks ‘Sleeping’ Genes—A Potential Cure for Prader-Willi Syndrome?

CRISPR epigenome editing successfully reactivates silenced genes in Prader-Willi Syndrome, highlighting potential for targeted therapies in genetic disorders.

20 Feb 2025

New Method Enables 20 Color Bioluminescent Imaging for Live Cells

Imaging live cells with fluorescent proteins has long been a crucial technique for understanding cellular behavior. While bioluminescent proteins offer several advantages over fluorescent proteins, the limited availability of color variants has made it difficult to observe multiple targets simultaneously.

23 Jan 2025

Is Calcium Signaling the Bridge Between Unicellular and Multicellular Life?

Calcium-dependent signaling in S. rosetta uncovers mechanisms of cellular coordination, shedding light on the evolution of multicellularity and sensory systems.

16 Jan 2025

Unveiling the Hidden Potential of SnoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

25 Nov 2024

Jackson ImmunoResearch Expands Product Line with Anti-GFP Antibodies

Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists seeking to harness the utility of the GFP (green fluorescent protein) tag.

25 Nov 2024

3D Tumor Microenvironment Model Highlights Role of Ischemia and Acidification in Cancer Spread

Developed 3MIC model simulates tumor microenvironments, enabling direct observation of ischemic effects on cancer cell invasiveness and drug resistance.

4 Nov 2024

Artificial Intelligence Designs Novel DNA Elements for Precise Gene Control

Using artificial intelligence, scientists at Yale University, the Broad Institute of MIT and Harvard, and The Jackson Laboratory have created thousands of novel DNA switches that can precisely regulate a gene's expression in many cell types.

24 Oct 2024

Scientists Develop Lab-Grown Muscle Stem Cells for Advanced Regenerative Therapies

Recent findings reveal that induced satellite cells can effectively regenerate muscle tissue, outperforming traditional myoblasts in engraftment and function.

23 Sep 2024

Bio-Rad Launches Annexin V StarBright Conjugates for Apoptosis Detection via Flow Cytometry

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIO.B), a global leader in life science research and clinical diagnostics products, today announced the launch of annexin V conjugated to eight StarBright Dyes: SBUV400, SBUV795, SBV440, SBV515, SBV790, SBB675, SBB765, SBY800. The new Annexin V StarBright conjugates support detection of early apoptotic cells by flow cytometry, offering an increased range of fluorophore options.

9 Aug 2024

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

The ability to alter or prevent the expression of faulty genes in the brain could be leveraged as a powerful therapeutic against neurodegenerative disease. However, the molecular underpinnings of the living brain are still largely inaccessible, hampering progress on such promising therapeutics.

9 Aug 2024

Researchers Recreate Chemically Regulated Actin Polymerization to Study Membrane Dynamics

A synthetic platform that uses dimerization modules consisting of chemical proteins to precisely control the polymerization of actin and demonstrate symmetry breaking.

19 Jun 2024

Single-Molecule Study Reveals Unexpected Role of Protein Stiffness in Nuclear Transport

The degree of softness or rigidity in specific regions of proteins can affect how quickly or slowly those proteins enter the nucleus, according to research from the Francis Crick Institute and King's College London.

14 May 2024

AI Predicts Mutations for Improved Protein Function

To design proteins with beneficial functions, researchers typically start with a natural protein possessing a desirable function, such as emitting fluorescent light.

5 Apr 2024

Retrotransposon-Based PRINT Technique Holds Potential for Precise Gene Insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

22 Feb 2024

APOE4's Influence on Lipid Droplets in Brain Cells

The largest genetic risk factor for late-onset Alzheimer's disease is apolipoprotein E (APOE), and researchers Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen group, have made a novel discovery about this protein.

12 Feb 2024

Study Investigates Antibiotic Resistance Genes Transfer Between Bacteria

A recent study reported in The Lancet Microbe reveals that the exchange of antibiotic resistance genes among diverse bacteria is significantly more extensive than previously believed.

11 Dec 2023

Biotium Launches New Line of Extensively Validated Primary Antibody Conjugates for Flow Cytometry

Biotium, a leading provider of innovative solutions for life science research, is thrilled to announce the launch of Biotium Choice primary antibody conjugates. With careful curation, and extensive in-house validation, Biotium Choice monoclonal primary antibodies are designed to deliver exceptional performance for flow cytometry.

From Biotium, Inc. 6 Dec 2023