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Complete Reference Genomes Unlocked for Six Ape Species

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee.

12 Apr 2025

Scientists Capture Dynamic Process of Chromatin Remodeling in Action

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases.

7 Apr 2025

New Tool Streamlines Genomic Research and Accelerates Medical Breakthroughs

A scientist from the School of Medicine, along with collaborators, has created a crucial new tool aimed at enhancing the efficiency of genomic research and expediting the development of innovative methods to improve human health.

28 Mar 2025

How Does DNA Unwind? Study Explores Helicase Mechanisms In DNA Replication

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights into viral replication mechanisms.

28 Mar 2025

Enhanced Embryo Screening Efficiency in Primate Genetic Modification

Genetic engineering in non-human primates has historically faced limitations due to the reliance on virus-based gene delivery methods.

26 Mar 2025

Visualizing the Fundamental Process of DNA Strand Separation

The exact moment DNA starts to unravel has been seen by scientists for the first time, exposing a chemical process that is essential for DNA to be the molecule that codes for all life.

20 Mar 2025

Researchers Develop RNA "Barcoding" Tool to Track Genetic Exchange in Bacteria

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems.

19 Mar 2025

Researchers Develop New Method for Assembling DNA Nanostructures

University at Albany researchers at the RNA Institute are pioneering new methods for designing and assembling DNA nanostructures, enhancing their potential for real-world applications in medicine, materials science and data storage.

13 Mar 2025

Lack of Genetic Diversity in Reference Groups Leads to Misdiagnoses

A new study has uncovered that a gene variant common in Oceanian communities was misclassified as a potential cause of heart disease, highlighting the risk of the current diversity gap in genomics research which can pose a greater risk for misdiagnosis of people from non-European ancestries.

8 Mar 2025

Mapping DNA's Hidden Switches: A Methylation Atlas

A new study, led by PhD student Jonathan Rosenski under the guidance of Prof. Tommy Kaplan from the School of Computer Science and Engineering and Prof. Yuval Dor from the Faculty of Medicine at the Hebrew University of Jerusalem and Hadassah Medical Center, has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types.

7 Mar 2025

New Genetic Discovery Could Lead to Larger Tomatoes and Eggplants

Bigger, tastier tomatoes and eggplants could soon grace our dinner plates thanks to Johns Hopkins scientists who have discovered genes that control how large the fruits will grow.

6 Mar 2025

Arab Pangenome Reference Provides New Path for Advancing Precision Medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

5 Mar 2025

New CRISPR Method Enhances Surveillance of Antibiotic Resistance in Wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

Unraveling PDMA's Influence on Rhizosphere Microbial Communities

The rhizosphere is influenced by a range of exudates released by plant roots. These root exudates serve as an “intermediary” between the plant and the soil, modifying the root's immediate environment.

3 Mar 2025

Novel Mechanism of mRNA Transfer via Tunneling Nanotubes Discovered

Cell-to-cell communication is crucial in all forms and stages of life, and various communication mechanisms have been extensively researched.

20 Feb 2025

Understanding the Complex Architecture of the Minor Spliceosome

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes – and it's doing this even as you read these lines.

13 Feb 2025

Scientists Discover Hidden Role of RNA Introns in Cellular Stress Response

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to oxidative stress.

12 Feb 2025

Researchers Cultivate an Ultrasmall Bacterial Strain Parasitizing Archaea

AIST researchers, in collaboration with JAMSTEC, Hokkaido University and Tohoku University, have succeeded in cultivating an ultrasmall bacterial strain parasitizing archaea and classified the strain PMX.108T as new species and genus of Minisyncoccus archaeiphilus.

11 Feb 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

Long-Read Sequencing Brings New Hope for Rare Disease Diagnosis and Treatment

One in every 10 people worldwide is impacted by a rare genetic disease but about 50% of them remain undiagnosed despite rapid increases in genetic technology and testing.

27 Jan 2025