Haematology News and Research

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CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

25 Apr 2023

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

31 Mar 2023

COVID-19 vaccines boost the levels of T cells in immunocompromised hematology patients

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

30 Mar 2023

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Mutations in the BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 persons, respectively, elevate the risk of various malignancies such as ovarian, breast, pancreatic, and prostate cancer considerably.

30 Nov 2022

Immunological mechanisms behind the development of alloantibodies

Hemophilia A is the most frequent severe variant of hemophilia. It nearly mostly affects men. The condition is frequently treatable, although not for all patients. A study at the University of Bonn has now highlighted a critical mechanism required for the therapy to be efficient.

28 Oct 2022

PhoreMost enters multi-project drug target discovery collaboration with Roche

PhoreMost to deploy its SITESEEKER platform to identify novel targets for Roche’s discovery programmes

From PhoreMost 6 Sep 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

Study sheds light on blood and immune systems development in prenatal bone marrow

Researchers carried out the first extensive investigation of the formation of the blood and immune systems in the prenatal bone marrow.

4 Oct 2021

Scientists are paving the way for cancer treatments with fewer side effects

In recent years, immunotherapy has revolutionized the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

5 Jul 2021

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

New analysis technique could pave way for major breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukaemia.

14 Dec 2020

Whole genome sequencing can improve rare disease diagnosis

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

25 Jun 2020