Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Researchers on the Brink of a Scientific Breakthrough in Cancer Treatment

By figuring out how the body’s immune system targets diseased cells, a multinational team of scientists is on the cusp of a breakthrough in the fight against cancer.

29 Aug 2024

Gut Microbiota Modulates Rotavirus Vaccine Effectiveness

Scientists at Georgia State University's Institute for Biomedical Sciences have shown that some gut flora can reduce the effectiveness of the rotavirus vaccine.

27 Aug 2024

Bad Bacteria Use Electric Signals to Find Entry Points in the Gut

How do bad bacteria find entry points in the body to cause infection? This question is fundamental for infectious disease experts and people who study bacteria.

21 Aug 2024

Mini-Gut Model Unlocks Secrets of COVID-19 Diarrhea

Researchers at Johns Hopkins Medicine claim to have identified multiple molecular pathways linked to diarrhea caused by COVID-19, offering possible therapeutic interventions utilizing human stem cells to create a sort of “mini intestine-in-a-dish.

7 Aug 2024

Uncovering the Molecular Mechanisms Underlying Liver Regeneration

The liver can renew itself quite well. Maintaining organ function and recuperating from surgery or injury depends on this quality. Using clinical samples, researchers from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthropology, TU Dresden, and ETH Zurich have examined the changes in liver cell types before and following regeneration.

31 Jul 2024

Federal Regulation Urged for Direct-to-Consumer Microbiome Tests

Scientific research has linked a person's microbiome to everything from gut and mental health to immunity and predisposition to cancer.

25 Mar 2024

Cholangiocarcinoma: New Organ-On-Chip Aims at Accelerating Research and Personalized Medicine

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it’s hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

23 Jan 2024

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

23 May 2023

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Researchers created organoids from cancer cells to reduce the need for trial and error in identifying effective cancer treatments in one of many cancer studies scheduled for presentation this week at Digestive Disease Week (DDW) 2023.

9 May 2023

Study Shows Profound Fluctuations in Gut Microbiome Throughout the Day and Across Seasons

The balance of microbes in the human gut varies substantially from morning to night and even more by season -; with profound fluctuations completely transforming the microbiome from summer to winter, according to a study to be presented at Digestive Disease Week 2023.

28 Apr 2023

Researchers Identify Novel Role of a Protein in the Development of Alcohol-Associated Liver Disease

Alcohol-associated liver disease (ALD), a complex disorder that occurs in some patients who have engaged in excessive alcohol use, is one of the leading causes of chronic liver disease among veterans and liver transplant patients in the United States.

19 Apr 2023

Small Vesicles Originating From Intestinal Bacteria Have an Adverse Effect on the Liver

Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites.

19 Apr 2023

Influence of molecular component of caffeine on gut health

Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).

16 Mar 2023

Study examines the role of dietary vitamin A in preventing or treating AAP

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

16 Mar 2023

Prolonged alcohol use and its detrimental effects on blood protein snapshot

Jon Jacobs, a biochemist, has examined the blood of people suffering from diseases including Ebola, cancer, TB, hepatitis, diabetes, Lyme disease, brain damage, and influenza.

10 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

Research highlights the new genetic variations and pediatric NAFLD severity

A multidisciplinary group of researchers at the University of California San Diego School of Medicine have advanced investigations into the genetic causes of NAFLD in children.

1 Jul 2022

Research highlights how microbe-free mice absorb fat using different sets of genes

According to a recent Duke research in mice, the microbes that assist break down food instruct the gut on how to do their job better.

18 May 2022