Immunology News and Research

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Immunology is the study of the body's immune system.

Novel Fungal Commensal Shaping Mouse Immune Responses

Researchers from Weill Cornell Medicine have found a fungus in the stomach of mice that may provide a clue to the evolution of fungi in the gastrointestinal tract.

28 Nov 2024

New Role for the Golgi Apparatus in Cancer Immunotherapy

The Golgi apparatus modifies, sorts, and packages proteins to be sent to their final destinations, whether that is within or outside of the cell.

25 Nov 2024

Mapping of Mouse Intestine Sheds Light on Immune Control and Adaptability

The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions such as celiac disease, ulcerative colitis, and Crohn's disease.

22 Nov 2024

New Insights Into Salmonella’s Ability to Manipulate the Gut Microbiota

Salmonella, a leading source of food poisoning, can enter the gut even in the presence of beneficial bacteria, according to a recent study from the University of California Davis Health.

18 Nov 2024

New Technology Isolates Key Gut Bacteria Linked to Disease

Researchers at UMC Utrecht have created a novel technique that effectively separates a particular subset of gut bacteria that are identified by IgA antibodies from fecal samples.

15 Nov 2024

Study Shows How Genetic Variations Can Enhance Cancer Drug Effectiveness

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

15 Nov 2024

New Strategy Reinvigorates Exhausted T Cells to Fight Cancer

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC Hillman Cancer Center.

11 Nov 2024

SARS-CoV-2 Outwits Immune System, Prolonging Infection

SARS-CoV-2 inhibits the function of the complement system, a crucial element of early antiviral immunity, by hijacking three crucial host proteins, according to research from the Medical Universities of Vienna and Innsbruck.

11 Nov 2024

Stem-Like CD4 T Cells Could Transform Cancer Treatment Strategies

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity.

28 Oct 2024

Cryo-EM Technology Paves the Way for Major Biological Discovery

Ben Orlando's research talk at MSU's Department of Biochemistry and Molecular Biology in 2019 laid the groundwork for a team effort that had been developing for decades.

25 Oct 2024

Study Reveals Role of Gut Microbes in Enhancing Children's Health

To address childhood malnutrition -; which affects 200 million children globally -; researchers at Washington University School of Medicine in St. Louis developed a therapeutic food that nourishes the collections of beneficial microbes that reside in the gut, and improves children's growth and other measures of their health.

25 Oct 2024

Light-Activated Immune Therapy Shows Promise Against Solid Tumors

Immunotherapies that mobilize a patient's own immune system to fight cancer have become a treatment pillar.

25 Oct 2024

Study Uncovers Mechanism Behind B-Cell Maturation in Leukemia

Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic Leukaemia (B-ALL) next year in Spain, according to the latest projections from the Spanish network of cancer registries (REDECAN).

23 Oct 2024

Study Identifies Novel Chromatin Configuration in Turtle Genomes

Researchers from UAB and Iowa State University have produced the first-ever genome assemblies of two hidden-neck turtle species.

22 Oct 2024

Disrupting a Gene Boosts T Cell Therapy, St. Jude Study Shows

Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most.

15 Oct 2024

Blood Vessel Cells Play a Crucial Role in Bone Development

Researchers have discovered a protein that inhibits the activity of bone-forming cells (osteoblasts) by preventing their maturation during the process of migrating to bone-formation sites.

14 Oct 2024

CAR-NKT Cells Show Promise in Overcoming Solid Tumor Barriers

Chimeric antigen receptor T-cell therapy (CAR-T) has shown significant promise in the treatment of blood malignancies in the fight against cancer.

8 Oct 2024

UNC Researchers Unveil CAR-NKT Therapy for Enhanced Antitumor Activity

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

8 Oct 2024

Fighting Drug-Resistant TB with a Novel Antibiotic

A novel semi-synthetic molecule that produces significant activity against strains of Mycobacterium tuberculosis, including those that are resistant to drugs, can be generated from natural compounds according to a study published in the American Society for Microbiology journal Microbiology Spectrum.

4 Oct 2024

Macrophage-Specific MAFB Deficiency Leads to Poor Prognosis in Acute Kidney Injury

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological activity and play a pivotal role in promoting and suppressing inflammation. Thus, elucidating their function is of paramount importance.

30 Sep 2024