Kidney News and Research

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Hepatitis E Virus Impairs Neuronal Cells, Reducing Neurite Length

For the first time, scientists can examine the effects of hepatitis E viruses on nerve cells using a novel cell model.

19 Nov 2024

Mouse Aging Proteomic Atlas Provides Insight into Age-Related Protein Shifts

With the worldwide population aging at an unprecedented rate, the prevention of age-related diseases has become a prominent issue.

18 Nov 2024

Comprehensive Proteomic Atlas of Aging in Mice

Preventing age-related illnesses has become a major concern as the global population ages at a never-before-seen rate.

15 Nov 2024

Caterpillar Fungus Compound Blocks Cancer Growth Signals Within 30 Minutes

Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for cell proliferation and survival.

15 Nov 2024

CRISPR Reveals Hidden Functions of Noncoding RNA

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from DNA to RNA to proteins.

8 Nov 2024

Unveiling the Protective Role of KLF6 in Diabetic Kidney Disease

Research by Stony Brook Medicine nephrology specialists may help prevent or reduce diabetic kidney disease progression by targeting cellular signaling between kidney cells and inducing a specific gene.

11 Oct 2024

A New Understanding of Chromatin Regulation and its Implications

Human survival is dependent upon an extraordinarily intricate dance that takes place inside every cell and every nucleus. DNA is continually being wrapped and unwrapped by proteins, and even small mistakes might result in cancer.

3 Oct 2024

Macrophage-Specific MAFB Deficiency Leads to Poor Prognosis in Acute Kidney Injury

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological activity and play a pivotal role in promoting and suppressing inflammation. Thus, elucidating their function is of paramount importance.

30 Sep 2024

Modified Nucleotides Boost saRNA Vaccine Efficacy and Protection Against SARS-CoV-2

Modified nucleotides like m5C in saRNA enhance vaccine efficacy, stability, and reduce inflammation, offering a promising approach for SARS-CoV-2 protection.

18 Sep 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

Study Reveals How Damaged Cells Contribute to Chronic Kidney Disease Progression

A study published in Nature Communications provides new insight into how damaged cells interact within disease-promoting microenvironments following acute kidney injury, or AKI.

6 Sep 2024

New AI Tool Predicts Protein Behavior in Cellular Context

A fish on land can still wave its fins, but the outcomes are very different when the creature is in water. The comparison, attributed to prominent computer scientist Alan Kay, is used to demonstrate the importance of context in clarifying research issues.

19 Aug 2024

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge.

24 Jul 2024

Study Shows the Ability of Protein 'Signatures' to Predict Onset of 67 Diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

24 Jul 2024

New ProteoCHIP EVO 96 Boosts Single-Cell Proteomics Sensitivity and Throughput

A label-free single-cell proteomics workflow that integrated the automated sample handling, optimal ion usage, and high-throughput capacities.

18 Jul 2024

Liver-on-Chips: Innovations, Applications, and Challenges in Drug Development

The development and application of liver-on-chips and the factors preventing its widespread use in drug discovery.

12 Jul 2024

Comprehensive Analysis Identifies Risk Factors for Multiple Cancers

Scientists have discovered over 5,000 genetic variations that give rise to specific cancers, along with a possible therapeutic target that could be used to treat or even stop these cancers from growing.

8 Jul 2024

Researchers Decode Impact of Every Possible Alteration in Critical Cancer Gene

Scientists at the Francis Crick Institute have mapped all possible outcomes of changes to a tumor-suppressing gene called VHL, as the first step in a massive research project to unravel the consequences of tens of thousands of genetic variations in genes linked to cancer.

4 Jul 2024

Study Uncovers a Biological Explanation for Long-Term Memories

Whether it's a first-time visit to a zoo or when we learned to ride a bicycle, we have memories from our childhoods kept well into adult years.

27 Jun 2024

Ultrasound-Triggered Nanodroplets for Targeted Drug Delivery

Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn’t needed – or where it even might cause harm.

22 Jun 2024