Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.
Bacteria shed membrane-enclosed tiny particles filled with proteins, lipids, DNA, RNA and metabolites. These particles, commonly known as bacterial extracellular vesicles (BEVs), are now being explored as possible tools for cancer diagnosis and treatment.
Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.
Loquat (Eriobotrya japonica) is an evergreen fruit tree whose winter growth and flowering make it especially vulnerable to sudden freezes.
Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases.
A metabolic byproduct formed when gut bacteria break down dietary fiber appears to protect against dangerous fungal infections common in immunocompromised patients, a study led by UT Southwestern Medical Center researchers shows.
A four-week, half-face clinical trial in 25 young Chinese women found that a moisturizer containing 5% fermented tea seed oil improved skin hydration, redness, and measured wrinkle appearance. Treatment was also associated with broader changes in skin lipid profiles and selected microbial taxa, although the study did not establish causality or compare fermented with unfermented tea seed oil.
An international study by scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the University of California, Los Angeles (UCLA) has identified a fundamental mechanism that regulates how the body uses stored fat to produce energy.
Researchers developed an eco-friendly workflow to recover squalene from wine lees using ultrasound-assisted extraction and convert it into more stable squalane using clay-supported palladium catalysts. The upcycled squalane showed improved oxidative stability and enhanced quercetin transport across an artificial membrane, supporting its potential as a sustainable cosmetic excipient.
What if the mechanical properties of a cell could be programmed like the components of a machine?
After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.
Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye.
A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, which have critical roles in biology.
This study was led by Prof. Jian Xu (Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences) in collaboration with Prof. Hongzhou Lu (Shenzhen Third People's Hospital) and Prof. Jiadong Huang (University of Jinan).
Lung cancer remains one of the world’s deadliest cancers, yet despite decades of effort to develop new drugs, many fail because they don’t stay in the body long enough to be effective or because they damage healthy organs.
A protein long studied for its connection to aging may also play a key role in protecting the body from chronic disease, according to new research from the laboratory of Mikhail Kolonin, PhD, published in Aging Cell.
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth beyond the capabilities of normal cells.
An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.
A protein found only in microscopic tardigrades, one that allows them to survive extreme conditions like dehydration, can convey similar durability in synthetic cells, according to new research from University of Michigan Engineering and the University of Chicago Pritzker School of Molecular Engineering.
Neural interaction with bacteria, e.g. in the gut microbiome, has important effects on brains of animals from worms to people.
Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment. However, evidence has recently emerged suggesting that these membranes do more than simply provide protection - they also influence the behavior of the protein receptors embedded in them.
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