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DNA Computing Circuits Move Closer to Real-Time Function Inside Living Cells

A comprehensive review titled "From the Test Tube to the Cell: A Homecoming for DNA Computing Circuits?" published Mar. 4 in Intelligent Computing, a Science Partner Journal, highlights progress in operating DNA computing circuits for operation within living cells.

9 Apr 2025

DNA Aptamers Offer Precision Attack Against Leukemia Stem Cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

4 Apr 2025

Allegro’s Injectable Osteoarthritis Treatment Generates Positive Safety Results in Preclinical Studies

Allegro NV, a biomedical company developing transformative nanotechnology-based treatments for degenerative joint disease, has found that hydrocelin (ALG-001), its injectable microparticle hydrogel, showed no signs of toxicity in two preclinical studies conducted for periods of 4 and 13 weeks respectively.

25 Mar 2025

Visualizing the Fundamental Process of DNA Strand Separation

The exact moment DNA starts to unravel has been seen by scientists for the first time, exposing a chemical process that is essential for DNA to be the molecule that codes for all life.

20 Mar 2025

Researchers Develop New Method for Assembling DNA Nanostructures

University at Albany researchers at the RNA Institute are pioneering new methods for designing and assembling DNA nanostructures, enhancing their potential for real-world applications in medicine, materials science and data storage.

13 Mar 2025

New Breakthrough Pushes DNA-Nanoparticle Motors Closer to Natural Protein Speed

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation.

23 Jan 2025

Scientists Discover Surprising Directional Flexibility in DNA-Shaping Motors

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction.

17 Jan 2025

Breakthrough in Nanopore Technology Could Transform Disease Detection

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

3 Jan 2025

Gradient Descent Approach to Optimizing AlphaFold2 Protein Predictions

Proteins are essential to human bodies as building blocks, transport systems, enzymes, and antibodies.

22 Nov 2024

Fermenting a Future for Food in Australia

Forming a National Food Plan and appointing a food minister are among the key recommendations of a white paper into growing a precision fermentation industry in Australia.

From University of Queensland 18 Nov 2024

Unlocking the Secrets of Life Through Synthetic Biology

It is one of the most fundamental questions in science: how can lifeless molecules come together to form a living cell? Bert Poolman, Professor of Biochemistry at the University of Groningen, has been working on this problem for over twenty years.

22 Oct 2024

How Comamonas Bacteria Transform Plastic Waste into Food

Researchers have long observed that a common family of environmental bacteria, Comamonadacae, grow on plastics littered throughout urban rivers and wastewater systems.

7 Oct 2024

Ribose-Water Interactions Stabilize RNA Structures

Ribonucleic acid (RNA) is a biological molecule that plays an important part in organismal genetics as well as the creation and development of life.

11 Sep 2024

A New Approach to Engineering Complex Organoids

A novel molecular engineering technology can precisely control the formation of organoids. Microbeads composed of precisely folded DNA are utilized to deliver growth factors or other signal molecules into tissue structures.

11 Sep 2024

New SPARXS Technique Revolutionizes DNA Sequence Analysis

"DNA, RNA and proteins are the key players to regulate all processes in the cells of our body," Leiden Professor John van Noort explains. "To understand the (mis-)functioning of these molecules, it is essential to uncover how their 3D structure depends on their sequence and for this it is necessary to measure them one molecule at a time. However, single-molecule measurements are laborious and slow, and the number of possible sequence variations is massive."

23 Aug 2024

Nutrient Nanomedicine Shows Promise Against Skin Cancer

An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells.

18 Jun 2024

Scientists Achieve Autonomous Control of Microscopic Machines

Tohoku and Kyoto University researchers have successfully created a DNA-based molecular controller that controls molecular robot building and disassembly autonomously.

17 Jun 2024

CRISPR/Cas Biosensors Address Sensitivity and Specificity Challenges in Detection

The mechanisms of CRISPR-Cas-based biosensors.

5 Jun 2024

DNA Origami Revolutionizes Cancer Immunotherapy: The DoriVac Breakthrough

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

New Nanotool Detects Pathogens at a Fraction of the Cost

A team of researchers from The University of Texas at Austin, led by SMU nanotechnology expert MinJun Kim, developed a less costly method to detect nuclease digestion, one of the essential processes in many nucleic acid sensing applications, such as those used to identify COVID-19.

14 Feb 2024