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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.

Melanin May Act as a "Drug Sponge," Influencing Medication Effectiveness

Skin pigmentation may act as a "sponge" for some medications, potentially influencing the speed with which active drugs reach their intended targets, a pair of scientists report in a perspective article published in the journal Human Genomics.

15 Oct 2024

UCI Researchers Receive $1.19 Million Grant to Unravel the Genetic Basis of Nicotine Addiction

A three-year, $1.19 million grant from the Tobacco-Related Disease Research Program will allow University of California, Irvine researchers to explore how specific sections of DNA might influence nicotine addiction.

26 Apr 2024

Oregon State Receives $7.5M Grant to Modernize Zebrafish Research Lab

Oregon State University has received a $7.5 million National Institutes of Health grant to modernize a lab focused on using zebrafish to address pressing human health challenges.

19 Sep 2023

Study finds similar levels of DNA damage in vapers and smokers

E-cigarettes-; used regularly by more than 10% of U.S. teens and more than 3% of adults-; were once pitched as a healthy alternative to tobacco cigarettes.

14 Feb 2023

The 12-hour cyclic gene activity abnormalities in schizophrenic brains

The first proof of 12-hour cycles of gene activity in the human brain is presented by researchers at the University of Pittsburgh School of Medicine in the United States.

From University of Pittsburgh 26 Jan 2023

FSU study shows the transgenerational transmission of aspartame-induced anxiety in mice

Florida State University College of Medicine researchers have linked aspartame, an artificial sweetener found in nearly 5,000 diet foods and drinks, to anxiety-like behavior in mice.

9 Dec 2022

16 distinct cell populations identified in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death.

From Institut Pasteur 15 Dec 2021

Battery-free, wearable device could quantify airborne nicotine exposure from e-cigarettes

Some studies have shown that nicotine, an addictive substance in electronic cigarettes, increases the risk of cardiovascular and respiratory disorders.

10 Dec 2021

DRI study receives $1.5M grant to investigate the formation of harmful compounds by e-cigarettes

Scientists with the Desert Research Institute Organic Analytical Laboratory in Reno, Nev., led by Andrey Khlystov, Ph.D., have been awarded a $1.5M grant from the National Institutes of Health (NIH) to study the formation of dangerous compounds by electronic cigarettes (e-cigarettes).

21 Jul 2021

Study compares effect of vaping and smoking on cells and DNA

Researchers have compared vape e-liquid samples and their aerosols to combustible cigarette smoke using Toxys’ ToxTracker range of in-vitro assays.

12 Apr 2021

Many light smokers meet the criteria for nicotine addiction

Even people who consider themselves to be casual cigarette smokers may be addicted, according to current diagnostic criteria. Researchers at Penn State College of Medicine and Duke University found that many light smokers -- those who smoke one to four cigarettes per day or fewer -- meet the criteria for nicotine addiction and should therefore be considered for treatment.

24 Dec 2020

Cocaine addiction: Impact of genetic mutations elucidated

Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available.

28 Sep 2020

Study shows strigolactones enhance tolerance to insects in tobacco plants

A team of researchers at the Max Planck Institute for Chemical Ecology in Jena, Germany, has discovered that strigolactones, a class of novel plant hormones, mediate the fine-tuning of the production plant defensive substances in the stem of plants of the wild tobacco species Nicotiana attenuata.

25 Aug 2020

Nicotine News and Research

Melanin May Act as a "Drug Sponge," Influencing Medication Effectiveness

UCI Researchers Receive $1.19 Million Grant to Unravel the Genetic Basis of Nicotine Addiction

Oregon State Receives $7.5M Grant to Modernize Zebrafish Research Lab

Study finds similar levels of DNA damage in vapers and smokers

The 12-hour cyclic gene activity abnormalities in schizophrenic brains

FSU study shows the transgenerational transmission of aspartame-induced anxiety in mice

16 distinct cell populations identified in a key brain region for substance use disorders

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

Battery-free, wearable device could quantify airborne nicotine exposure from e-cigarettes

DRI study receives $1.5M grant to investigate the formation of harmful compounds by e-cigarettes

Study compares effect of vaping and smoking on cells and DNA

Many light smokers meet the criteria for nicotine addiction

Cocaine addiction: Impact of genetic mutations elucidated

Study shows strigolactones enhance tolerance to insects in tobacco plants

Long-term opioid use in back-pain patients leads to production of anti-opioid antibodies

Researchers are testing new way to deliver vaccines through microneedle skin patches

New method imitates how plants produce hormones

Smokers More Likely To Express ACE2 Protein That SARS-COV-2 Uses

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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