Premature ovarian failure (POF) is a condition that is characterized by the ovaries ceasing to function before the age of 40. This is distinct from premature menopause as women still have an occasional period and it is possible for them to get pregnant. POF affects approximately 1 in 100 women of childbearing age younger than 40 years old.
The biological foundations of a reproductive disease caused by a DNA mutation have been discovered by a University of California, Riverside study. Fragile X Syndrome, a major genetic contributor to cerebral impairment and autism, is also caused by this gene mutation.
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