Progenitor Cells News and Research

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Study Sheds Light on Development and Evolution of the Human Hypothalamus

The hypothalamus is a small but critical region at the base of the brain that controls the autonomic nervous system, regulates body temperature, signals hunger and thirst, exerts hormonal control over the pituitary gland, helps set circadian rhythms, influences sexual behavior and reproduction, and plays a role in instinctive behaviors like fear, aggression, and maternal bonding.

9 Apr 2025

Placenta-Derived Signals Improve Liver Organoid Size and Function

Organoids, which are designed to mimic human organs, hold promise for both research and treatment;

9 Apr 2025

Scientists Discover Key Genes for Regenerating Sensory Cells in the Ear and Eye

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the National Academy of Sciences.

1 Apr 2025

Dual Gene Role in Brain Progenitor Cell Dynamics

Scientists have uncovered a crucial genetic mechanism that plays a key role in the development and evolution of the human brain.

27 Mar 2025

Can Tissue Engineering and Regenerative Medicine Reverse Spinal Cord Injuries?

Advances in tissue engineering offer hope for spinal cord injury repair, utilizing biomaterials, stem cells, and bioactive molecules to promote regeneration.

20 Mar 2025

Scientists Uncover Circuit Controlling Neuron Migration in Brain Development

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

10 Jan 2025

Stress Pathway in Microglia Found to Contribute to Alzheimer's Neurodegeneration

Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD).

26 Dec 2024

New iFlpMosaics Toolkit Enhances Gene Research and Disease Insights

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

14 Dec 2024

Insights into Neurodegenerative Diseases and Pest Control

Key gene regulators that allow certain deafened animals, such as fish and lizards, to naturally regenerate their hearing have been identified by a recent USC Stem Cell study that was published in the journal Proceedings of the National Academy of Sciences (PNAS).

10 Dec 2024

New Insights into How Plants Regulate Growth and Development

Plants form new leaves, flowers and roots at the tips of shoots and roots, in specific growth regions known as meristems. These meristems contain stem cells that divide as needed and form new cells that develop into specialized tissue.

15 Oct 2024

New RNA Molecule Found to Boost Wound Healing

A new study from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing. The research, published in Nature Communications, may have implications for the treatment of hard-to-heal wounds.

9 Oct 2024

Tuft Cells: A New Hope for Gut Healing

Immunological cues cause intestinal tuft cells to proliferate and create new cells. Furthermore, tuft cells can withstand severe damage, such as radiation damage, and aid in the regeneration of the epithelium, in contrast to progenitor- and stem cells.

3 Oct 2024

From Bone Regeneration to Heart Repair: Stem Cell Transplantation Paves the Way for New Medical Frontiers

Stem cell transplantation offers promising solutions for tissue regeneration and age-related degeneration, despite challenges in safety and production costs.

9 Sep 2024

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

New Population of Cells in Human Omental Fat Tissue Found to Hinder Adipogenesis

Understanding how fat tissue forms and functions is crucial for addressing obesity and related metabolic diseases. However, adipose tissue, or body fat, behaves differently based on its location in the body.

10 May 2024

Research Sheds Light on Blood Cell Production in Mouse Skeleton

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.

25 Mar 2024

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024

The Role of Ancient Retroviruses in Vertebrate Brain Evolution

According to a study published in the journal Cell, ancient viruses may have contributed to the development of myelin and, consequently, the large, complex brains.

16 Feb 2024

Safer and More Effective Cell Therapy for Spinal Cord Injuries

For patients with spinal cord injuries, a small gadget developed by researchers at MIT and the Singapore-MIT Alliance for Research and Technology may help to increase the efficacy and safety of cell therapy treatments.

8 Feb 2024

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

5 Jan 2024