Protein Engineering News and Research

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Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

A revolution in biomedicine is currently underway, driven by the application of genome engineering tools such as the prokaryotic CRISPR-Cas9.

3 Oct 2024

DeepEvo: Revolutionizing Protein Engineering with Artificial Intelligence

Engineering proteins for desirable traits has been the holy grail of modern biotechnology.

1 Jul 2024

Rice Study Sheds Light on Pseudogene Dynamics

Rice University's Peter Wolynes and his research team have unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve.

14 May 2024

Novel Molecule Targets Coronavirus and Boosts Antiviral Drug

Following the COVID-19 pandemic, researchers have been working hard to create antiviral medications and treatments.

15 Mar 2024

AI's Impact on Protein Function Prediction Revealed

Researchers may be able to learn more about the inner workings of cells with the aid of a novel artificial intelligence (AI) technology that makes logical deductions regarding the function of unidentified proteins.

15 Feb 2024

New Microbe Offers Economical Solution for Synthetic Biological Experiments

Cornell University researchers have created a new version of a microbe to compete economically with E. coli – a bacteria commonly used as a research tool due to its ability to synthesize proteins – to conduct low-cost and scalable synthetic biological experiments.

14 Feb 2024

Johnson Matthey Announces Partnership With Basecamp Research to Accelerate the Adoption of Biocatalysis Solutions

Johnson Matthey (JM), a global leader in sustainable technologies, and Basecamp Research, a leader in mapping biodiversity for computational bio-design, today announced their partnership to accelerate the adoption of more sustainable, bio-based catalysts.

From Johnson Matthey 5 Dec 2023

Leveraging Nature's Blueprint: The Impact of Directed Evolution in Protein Engineering

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Miguel Alcalde, a Research Professor at the CSIC, about directed evolution in enzymology and the wider biotechnology sector.

From Society for Laboratory Automation and Screening (SLAS) 4 Aug 2023

Breakthrough in Single-Cell Genome Sequencing: New Method Reduces Bias and Expands Research Horizons

It has long been technically difficult to sequence the genome of a single bacterial cell due to the nearly impossible bias in the gene amplification stage of the process, making it difficult to produce a high-coverage genome sequence from precisely one bacterial cell.

25 Jul 2023

Scientists Develop Method to Create Artificial Allosteric Sites in Protein Complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

7 Jul 2023

New AI-Assisted Methods to Discover Novel Deaminase Proteins with Unique Functions

At the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, GAO Caixia’s group has introduced the use of artificial intelligence (AI)-assisted techniques to find out novel deaminase proteins with special functions via structural prediction and classification.

28 Jun 2023

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

28 Apr 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

AI develops first-ever functional artificial protein

Scientists have developed an AI system that can produce artificial enzymes from scratch. Even though several of these enzymes’ artificially generated amino acid sequences differed noticeably from those of any known natural protein, they nonetheless performed as well in laboratory testing as those found in nature.

27 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

Small fluorescent protein helps researchers to capture deeper, more precise biomedical images

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

7 Dec 2022

Preventing protein-protein interactions with a new tool

Proteins constantly interact with one another inside cells to perform various tasks. Blocking the binding of two or more proteins appears as a potential treatment for some diseases where these functions are altered.

1 Dec 2022

Researchers introduce CRISPR to enable gene editing in cockroaches

According to a study released by Cell Press on May 16th, 2022, in the journal Cell Reports Methods, scientists have created a CRISPR-Cas9 technique to facilitate gene editing in cockroaches.

23 May 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

Evonetix granted patent for technology enabling thermally-controlled DNA synthesis

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced it has been granted patent EP3551331B1 in Europe for its proprietary thermal control technology for DNA synthesis, as well as the design and manufacture of its silicon chips.

From Evonetix 4 Apr 2022