Protein Synthesis News and Research

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How CRISPRi is Helping Combat Drug-Resistant Tuberculosis

Findings on isoniazid-resistant M. tuberculosis reveal key vulnerabilities, suggesting new avenues for treatment strategies against drug-resistant tuberculosis.

20 Nov 2024

Unveiling the Mechanisms of Phenotypic Heterogeneity in M. tuberculosis

The only single-celled organism ever found to sustain a steady growth rate throughout its life cycle is the rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again named the leading infectious disease killer worldwide.

18 Nov 2024

New Insights into the Molecular Basis of Mitochondrial Diseases

A significant finding about the energy production process of human cells has been made by researchers at the Karolinska Institute's Department of Cell and Molecular Biology.

11 Nov 2024

Domainex Integrates Nuclera’s eProtein Discovery System to Enhance Drug Discovery Services

Nuclera, the biotechnology company accelerating protein expression and optimization through its benchtop eProtein Discovery™ system, and Domainex, a multi-award winning provider of integrated, pre-clinical drug discovery services, today announced that Domainex is the first contract research organization (CRO) to have installed the eProtein Discovery system and offer protein production services using the technology.

9 Nov 2024

Unlocking the Secrets of Life Through Synthetic Biology

It is one of the most fundamental questions in science: how can lifeless molecules come together to form a living cell? Bert Poolman, Professor of Biochemistry at the University of Groningen, has been working on this problem for over twenty years.

22 Oct 2024

A Novel Regulator of RNA Processing in Alzheimer's Disease

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that modifies the process of protein synthesis and impacts RNA processing in Alzheimer's patients' brains.

21 Oct 2024

Placental Protein Levels Offer Insights into Early-Onset Preeclampsia

A potentially fatal pregnancy complication, preeclampsia is characterized by persistently elevated blood pressure, which is exacerbated when it develops early in the first trimester.

15 Oct 2024

A Novel Method for Incorporating Non-Canonical Amino Acids into Proteins

Every basic biology lesson teaches that proteins are made up of combinations of 20 distinct amino acids, which are ordered in various patterns similar to words.

12 Sep 2024

A Powerful New Tool for Biomedical Research

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have built a comprehensive molecular map of the human body and its complicated physiological processes by analyzing thousands of molecules found in 391 volunteers' blood, urine, and saliva samples.

12 Sep 2024

New Insights into Python Cardiac Biology Could Inform Human Heart Disease Research

Study of python cardiac responses to feeding uncovers structural and epigenetic changes, enhancing understanding of heart disease and therapeutic applications.

2 Sep 2024

The Influence of 'Silent' Mutations on Genetic Disorders

Genetic disorders -; like cystic fibrosis and Huntington's disease -; are considered incurable, with gene mutations occurring in essentially every cell of the body.

29 Aug 2024

Light-Activated Macrophages Show Increased Appetite for Cancer Cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

13 Aug 2024

UCL Scientists Uncover New Role of Ribosomes in Protein Folding

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.

8 Aug 2024

Innovative Approach to Protein Synthesis Funded by $2 Million Grant

The National Institutes of Health's Maximizing Investigators' Research Award (MIRA) program for established investigators has awarded Rice University chemist Han Xiao with nearly $2 million.

4 Jul 2024

Unlocking the Secrets of Aging Brains

Researchers have determined the potential mechanisms through which some long-lived mutants of the Caenorhabditis elegans model system experience cognitive decline and others can retain learning and memory into old age.

26 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

Protein Complex Movement May Regulate Cell Division, Impacting Disease Research

Scientists at Umeå University in Sweden have found that the movement of a unique protein complex known as the Mediator along DNA genes may affect the process of cell division.

6 May 2024

Protein TRBP's Regulatory Role in Immune Response to Viral Infections Uncovered

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

22 Apr 2024

New Theory Links Gene Length to Cellular Decline

A gene’s length may have more to do with aging than particular “aging genes.” Reduced expression of long genes may be the cause of many aging-related changes, according to researchers writing an opinion piece that was published in the journal Trends in Genetics on March 21st, 2023.

25 Mar 2024

Researchers Create Groundbreaking RNA and DNA Solutions to Shield Plants from Viral Attacks

Customized RNA or DNA molecules have been shown to effectively combat viral infections in plants, as demonstrated in a recent study conducted by Martin Luther University Halle-Wittenberg (MLU) and published in the International Journal of Molecular Sciences.

1 Mar 2024