Ribosome News and Research

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Meet Lariocidin: A Game-Changing Antibiotic That Outsmarts Resistance

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant bacterial infections effectively.

4 Apr 2025

Lariocidin Peptide Shows Promise as Novel Antibiotic for Fighting Infections

A small molecule shaped like a lasso may be a powerful tool in the fight against infectious diseases, according to a new study in Nature co-authored by University of Illinois Chicago researchers.

27 Mar 2025

Circular RNA's Transformative Role in Tumor Biology and Treatment

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

10 Mar 2025

Breakthrough mRNA Technology Paves the Way for Precision Medicine

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

20 Feb 2025

Microscopy Technique Tracks Ribosome Activity

A novel microscopy method has been created by researchers from the Tanenbaum group at the Hubrecht Institute to view the activity of ribosomes in cells.

3 Feb 2025

Compound from Sea Sponge Could be Used as a Chemical Probe for Research

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects.

15 Jan 2025

High-Resolution Technique Maps Ribosome Elongation Cycle

At one time or another, most of us have played with a flipbook, using our thumbs to rapidly flip a series of pictures to create an illusion of movement.

20 Dec 2024

New Virus Found to Alter Cell Machinery in Eukaryotic Cells

Julie Thomy, lead author of the study and postdoctoral researcher in the Daniel K. Inouye Center for Microbial Oceanography: Research and Education (C-MORE) and Department of Oceanography in the UH Mānoa School of Ocean and Earth Science and Technology (SOEST)

18 Dec 2024

Ribosomal Fingerprints: A Novel Approach to Early Cancer Detection

Different types of cancer have unique molecular 'fingerprints' which are detectable in early stages of the disease and can be picked up with near-perfect accuracy by small, portable scanners in just a few hours, according to a study published today in the journal Molecular Cell.

11 Dec 2024

Novel Approach to Monitor ER-Related Protein Quality Control

Protein synthesis in eukaryotic cells found in plants, animals, and fungi involves more than just the straightforward ribosome assembly of amino acids.

9 Dec 2024

Bacteria Alter Ribosomes to Resist Common Antibiotics

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications.

2 Dec 2024

The Role of RNA Polymerase and Ribosomes in Gene Expression

DNA within a cell contains the genetic instructions necessary for building proteins.

29 Nov 2024

Magnesium-Focused Approach to Curbing Antibiotic Resistance

According to recent estimates, the number of fatal antibiotic-resistant illnesses is expected to increase significantly over the next 25 years.

18 Nov 2024

Monoclonal Antibody Market Set to Triple by 2033, Revolutionizing Disease Treatment

Recent advancements in monoclonal antibody engineering are reshaping disease treatment, focusing on safety, effectiveness, and addressing current medical needs.

28 Oct 2024

How Cancer Cells Use Ribosomes to Evade the Immune System

The protein factories of our cells are much more diverse than we thought they were. Scientists from the Netherlands Cancer Institute have now shown that cancer cells can use these so-called ribosomes to boost their invisibility cloak, helping them hide from the immune system.

22 Oct 2024

A Novel Regulator of RNA Processing in Alzheimer's Disease

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that modifies the process of protein synthesis and impacts RNA processing in Alzheimer's patients' brains.

21 Oct 2024

AI-Driven Insights into Lasso Peptide Biosynthesis

Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tested models for how these peptides are made and demonstrated how this information might be used to advance lasso peptide-based drugs into the clinic.

23 Sep 2024