Stavudine, also known as Zerit or d4T, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). This class of medicines blocks reverse transcriptase, a protein that HIV needs to make more copies of itself. Stavudine was approved by the FDA on June 24, 1994, for use in combination with other antiretroviral agents for the treatment of HIV infection in adults and children. Stavudine may also be used to prevent health care workers and others from getting HIV infection after they accidentally come into contact with the virus on the job; however, this practice does not have FDA approval. Stavudine does not cure or prevent HIV infection or AIDS and does not reduce the risk of passing the virus to other people.
A protein known as polymerase is used by SARS-CoV-2—the coronavirus that is responsible for causing the worldwide COVID-19 pandemic—to replicate its genome within the infected human cells.
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