Vaccine News and Research

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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Thermo Fisher Scientific and Chan Zuckerberg Institute for Advanced Biological Imaging Collaborate to Further Understanding of Human Cells

Thermo Fisher Scientific Inc., the world leader in serving science, has announced a Technology Alliance Agreement with the Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute).

28 Mar 2025

How B Cells Know When to Mutate—and When to Chill

Study reveals B cells suppress mutations during rapid division, enhancing immune response and offering critical insights for vaccine and treatment development.

27 Mar 2025

Zika and Dengue Virus Use Different Strategies to Infect Dendritic Cells

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

26 Mar 2025

Unveiling Bacterial Immune Mechanisms Against Temperate Phages

Like humans, bacteria can be attacked by viruses. In the case of bacteria, these viral attackers are referred to as bacteriophages, a term derived from the Greek word for bacteria-eaters, or simply “phages.”

24 Mar 2025

New Insights into How B Cells Strategically Clone High-Affinity Antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

20 Mar 2025

Study Finds Key Mechanism Behind Plasma Cell Migration for Lasting Immunity

Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections.

13 Mar 2025

$30 Million Grant Supports AI-Powered Antibody Therapy Development

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

10 Mar 2025

Dual Antibodies Found to Combat All SARS-CoV-2 Variants

A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep pace with evolving viruses.

6 Mar 2025

Researchers Develop Mycobacteria Strains with Kill Switches for Safer TB Vaccines

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.

26 Feb 2025

T Cells May Hold the Secret to Fighting Dengue Virus

Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study led by scientists at La Jolla Institute for Immunology (LJI).

25 Feb 2025

New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025

New Method Helps Detect Mutations Causing Immune Escape in Viruses

Viruses are masters at disguise. When they are pushed too far by our immune system, they send new virus variants into play that are no longer recognized by immune cells.

31 Jan 2025

Leveraging AI to Aid the Development of T Cell Vaccine Candidates

An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell vaccine candidates.

29 Jan 2025

New Method Helps T Cells Live Longer and Fight Cancer More Effectively

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

29 Jan 2025

Mapping the Human Virome to Uncover Links Between Viruses and Health

You, my friend, are what scientists call a "holobiont"- an organism made up of human cells and the multiplicity of microscopic species living inside you and on your body.

27 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Is it possible to predict a pathogen’s next move? Novel tool for detecting pathogen fitness says yes!

Phylowave reveals evolutionary dynamics in pathogens, identifying fitness-linked lineages and mutations, essential for effective public health interventions.

13 Jan 2025

Study Reveals T Cells as Key Players in Complete Viral Infection Control

Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that T cells-white blood cells that can destroy harmful pathogens-can completely prevent viral infection, to an extent previously thought only possible due to neutralizing antibodies.

13 Jan 2025

NIH Study Reveals Potent Antibodies for Malaria Prevention

A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods, according to a study from researchers at the National Institutes of Health (NIH) published today in Science.

6 Jan 2025

Novel Vaccine Adjuvant with Potent Immunostimulatory Properties

Researchers from JCU have discovered particles in the well-known “superfood” spirulina that may significantly improve the efficacy and production of vaccines.

3 Jan 2025