Vascular News and Research

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Novel Approach to Isolating and Quantifying EV Cargo for Disease Diagnosis

Parkinson's disease (PD) and Alzheimer's disease (AD) are examples of brain illnesses that begin to develop in patients far earlier than the onset of their initial clinical symptoms.

4 Nov 2024

New Protein Identified in Ferns Reveals Role in Plant Gender and Stem Cell Control

Purdue University plant scientists have identified a protein that plays a previously unknown role in controlling cell differentiation and determining gender in vascular plants, using a fern model.

13 Sep 2024

SGLT-2 Inhibitors May Lower Dementia Risk in Type 2 Diabetes Patients, Study Finds

A study reveals SGLT-2 inhibitors significantly reduce dementia risk in type 2 diabetes patients, with effects strengthening over longer treatment durations.

9 Sep 2024

CRISPR/Cas System Revolutionizes Tumor Variant and Biomarker Detection

The CRISPR-Cas system is transforming tumor biomarker detection, enabling ultra-sensitive diagnostics and improving accuracy in cancer detection and monitoring.

4 Sep 2024

Single-Cell Sequencing Reveals Mechanism of Coronary Artery Formation

The process by which new arteries develop in the heart has been clarified by a group under the direction of Dr. Elena Cano at the Integrative Vascular Biology Lab of Professor Holger Gerhardt at the Max Delbrück Center in Berlin.

2 Sep 2024

Study Uncovers Biomarkers for Low Muscle Mass, Offering Insights for Personalized Prevention

Machine learning models to analyze computed tomography (CT) images of the chest and a proteomics approach to determine blood protein biomarkers.

15 Aug 2024

Uncovering the Molecular Mechanisms Underlying Liver Regeneration

The liver can renew itself quite well. Maintaining organ function and recuperating from surgery or injury depends on this quality. Using clinical samples, researchers from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthropology, TU Dresden, and ETH Zurich have examined the changes in liver cell types before and following regeneration.

31 Jul 2024

New Research Highlights Brain Connectivity as Key Factor in Cognitive Aging

How variations in cognitive abilities, cognitive reserve, and SVD-related neuropathologies impacted SFC in aging adults.

22 Jul 2024

New Insights into the Composition and Efficacy of Stem Cell Therapies

Two commonly used stem cell therapies are found to contain entirely different types of cells, despite their frequent interchange, according to research from the University of California San Diego.

15 Jul 2024

Harnessing Enzymes for Making RNA Therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

15 Jul 2024

Liver-on-Chips: Innovations, Applications, and Challenges in Drug Development

The development and application of liver-on-chips and the factors preventing its widespread use in drug discovery.

12 Jul 2024

Unlocking the Spatial Dynamics of Amino Acid Metabolism in Tea Plants

Amino acids are vital for plant growth and significantly influence tea flavor and health benefits. Tea plants, particularly Camellia sinensis, exhibit unique amino acid profiles that contribute to their distinctive taste and nutritional value.

25 Jun 2024

Stem cell-based kidney chip revolutionizes disease modeling and research

An organ-on-chip system containing a kidney glomerulus using human-induced pluripotent stem cells and an ultrathin membrane.

17 Jun 2024

"Cervix-on-a-Chip" Offers Promise for New Bacterial Vaginosis Treatments

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

3 Jun 2024

Largest Plant DNA Study Ever Unveils Flowering Plant Tree of Life

The most up-to-date understanding of the flowering plant tree of life is presented in a new study published today in the journal Nature by an international team of 279 scientists, including three University of Michigan biologists.

25 Apr 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

Cryo-EM Imaging Unveils Similar Protein Structures in Alzheimer's and Down Syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

30 Mar 2024

New Study Sheds Light on Blood-Brain Barrier Dysfunction in Aging

The central nervous system requires a tightly controlled environment for the neurons in the brain to function properly and be able to process information. The blood-brain barrier, which is maintained by specific brain endothelial cells lining blood vessel inner walls, controls the exchange of chemicals between the neurological and circulatory systems.

25 Mar 2024

DNA Origami Revolutionizes Cancer Immunotherapy: The DoriVac Breakthrough

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Biological Glue Provides Clues About Cardiovascular Diseases

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

12 Mar 2024