Cell Biology

RSS

Analyses of DNA tags may lead to better understanding of treatment approaches for cancers

Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s but with rapid advances in genomics and computational analytics in just the past few years, researchers at Georgetown Lombardi Comprehensive Cancer Center now believe that studying tags, or modifications to this type of DNA, may lead to a better understanding of how to assess, and possibly modulate, treatment approaches for cancer and other diseases.

28 Jul 2021

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord.

28 Jul 2021

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

T cell-depleted macaques can mount potent memory responses against SARS-CoV-2

New research conducted in monkeys reveals that T cells are not critical for the recovery of primates from acute COVID-19 infections.

28 Jul 2021

New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

Study proposes methods to purge unstable regulatory T cells

Scientists from the Babraham Institute, United Kingdom and VIB-KU Leuven, Belgium, came up with two solutions that can overcome a major clinical limitation of immune cell therapies. The researchers chose mice as their model. The findings were published recently in the journal Science Immunology.

27 Jul 2021

New thin-film microfluidic device to manipulate β-lactoglobulin in milk

Researchers have manipulated beta-lactoglobulin, or β-lactoglobulin, by using an Australian-made innovative thin-film microfluidic device.

27 Jul 2021

Study unravels novel centromeric functional protein

Scientists have discovered a new centromeric functional protein and dubbed it Adaptor of polo1 (Apolo1). The findings of the study were reported in Cell Reports.

27 Jul 2021

Researchers develop repository showcasing antibody activity on spike protein variants

Scientists have created an “atlas” that charts how 152 different antibodies attack a major piece of the SARS-CoV-2 machinery, the spike protein.

27 Jul 2021

Pushing organ-on-a-chip microdevices to new levels to improve ovarian cancer treatment

In the evolving field of cancer biology and treatment, innovations in organ-on-a-chip microdevices allow researchers to discover more about the disease outside the human body.

26 Jul 2021

Study identifies the role of lysosomes in the spread of Parkinson’s disease

In the past few decades, neurodegenerative diseases have turned into one of the top 10 worldwide causes of death.

26 Jul 2021

Study reveals the role of transcription in shaping the genome

Developments in the field of microscopy allowed scientists to picture loops of DNA strands for the first time.

26 Jul 2021

Study employs llama nanobodies to hunt human cytomegalovirus

Researchers created a “nanobody”, a small fragment of a llama antibody, that can evade human cytomegalovirus as it hides away from the immune system.

26 Jul 2021

Stiffness of protein fibers plays a key role in controlling cell movement, study shows

A new study, led by University of Minnesota Twin Cities engineering researchers, shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells.

23 Jul 2021

Cell-analysis method could pave the way for new strategies to fight tuberculosis

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.

23 Jul 2021

Already characterized active substances exhibit unexpected effects

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

New insights on an enzyme complex involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

Research identifies vitamin C as a key ingredient for immune cell function

A new study has now identified that it is not possible to generate stable regulatory T cells without Vitamin C or enzymes called TET proteins as much as how one cannot make a banana split without bananas.

23 Jul 2021

Cell Biology

Analyses of DNA tags may lead to better understanding of treatment approaches for cancers

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Study: Biomarker can predict response to immunotherapies in breast cancer patients

T cell-depleted macaques can mount potent memory responses against SARS-CoV-2

New formulation to administer antibodies for choroidal neovascularization therapy

Study proposes methods to purge unstable regulatory T cells

New thin-film microfluidic device to manipulate β-lactoglobulin in milk

Study unravels novel centromeric functional protein

Researchers develop repository showcasing antibody activity on spike protein variants

Pushing organ-on-a-chip microdevices to new levels to improve ovarian cancer treatment

Study identifies the role of lysosomes in the spread of Parkinson’s disease

Study reveals the role of transcription in shaping the genome

Study employs llama nanobodies to hunt human cytomegalovirus

Stiffness of protein fibers plays a key role in controlling cell movement, study shows

Cell-analysis method could pave the way for new strategies to fight tuberculosis

Already characterized active substances exhibit unexpected effects

New insights on an enzyme complex involved in plaque production

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

Research identifies vitamin C as a key ingredient for immune cell function

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics