Cell Biology

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Scripps Research Unveils Brain Neurons That Control First Bite and Drinking Behavior

Do you grab a fork and take a first bite of cake, or say no and walk away? Our motivation to eat is driven by a complex web of cells in the brain that use signals from within the body, as well as sensory information about the food in front of us, to determine our behaviors.

12 Jul 2024

AI-Driven Atlas Reveals Hidden Proteins in Cellular Condensates

Scientists at the University of Cambridge have developed an atlas of proteins describing how they behave inside human cells.

11 Jul 2024

Key Brain Cells Discovered in Delaying First Bite of Food

Scientists at Scripps Research have pinpointed a group of neurons in the previously overlooked parasubthalamic nucleus (PSTN) that govern the initiation of feeding behavior.

11 Jul 2024

Kainate Receptors: A Potential Target for Novel Cerebellar Therapies

The Institute of Neurosciences (IN), a collaborative center of the Miguel Hernández University (UMH) of Elche and the Spanish National Research Council (CSIC) is leading a study in Tokyo, Japan, in conjunction with Keio University, which highlights the critical role one of the glutamate receptors plays in the proper functioning of the cerebellum's synapses.

11 Jul 2024

Liver Blood Vessels Trigger 'Sleep Timer' to Inactivate Immune Cells in Chronic Hepatitis B

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive.

11 Jul 2024

Phage-Derived Endolysin Offers Targeted Treatment for Dysbiosis-Driven Acute GVHD

Allogenic hematopoietic cell transplantation (allo-HCT) involves transferring healthy donor stem cells to recipients with conditions like blood cancer, bone marrow failure, or certain genetic blood disorders.

11 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Researchers Uncover Bacterial Alarm Mechanism Against Antibiotics

When confronted with an antibiotic, toxic substance, or other source of considerable stress, bacteria are able to activate a defense mechanism using cell-to-cell communication to 'warn' unaffected bacteria, which can then anticipate, shield themselves and spread the warning signal.

11 Jul 2024

UNC-Chapel Hill Study Reveals New Mechanism of Gene Regulation Beyond Histone Modification

University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation according to the paper, "Drosophila melanogaster Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation," published in Genes & Development.

11 Jul 2024

Unveiling the Genetic Secrets of Bacterial Iridescence

An international team of researchers has investigated the mechanism that makes some types of bacteria reflect light without using pigments.

10 Jul 2024

Real-Time Snapshots of RNA Polymerase Illuminate Transcription Bubble Dynamics

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA.

10 Jul 2024

Retron-Based Tool Enables Multi-Site DNA Editing

Genome editing has become a widely adopted technology to modify DNA in cells, allowing scientists to study diseases in the lab and develop therapies that repair disease-causing mutations.

10 Jul 2024

Unveiling the Power of mRNA and LNPs in Modern Medicine

Consider a situation in which an expert hacker has to upload vital software to update a central server and stop a potentially fatal virus from causing havoc on a sizable computer network.

10 Jul 2024

Unveiling Progesterone's Impact on Cancer Immunosuppression

Researchers turned to pregnancy to explore why some cancers successfully evade the immune system and grow unchecked.

9 Jul 2024

New Guidelines Address Ethical Concerns of Stem Cell Embryo Research in the UK

The UK’s first guidelines for research with stem cell-grown embryo models state that all studies involving these models should be overseen by a dedicated committee.

8 Jul 2024

Scientists develop first fully functional human immune system in mouse model

Researchers at The University of Texas Health Science Center in San Antonio have produced a mouse model that is humanized, complete with a human immune system and a gut microbiome that resembles that of a human being and is able to elicit particular antibody responses.

8 Jul 2024