Cell Biology

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Researchers discover signaling pathway that can regulate beige fat thermogenesis

Researchers have discovered a new set of signals that cells send and receive to prompt one type of fat cell to convert fat into heat.

12 Jun 2020

Cardiac organoids that closely mimic physiological conditions during a heart attack

In the U.S., someone has a heart attack every 40 seconds, and yet researchers have not had a model that fully mimics what occurs in the human heart after a heart attack.

12 Jun 2020

Human stem cell models reveal neurodegeneration in glaucoma

Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.

12 Jun 2020

Researchers create a new model to study early stage of human development

Researchers from the University of Cambridge have devised a new model to analyze an early stage of human development through human embryonic stem cells.

12 Jun 2020

Excessive degradation of mitochondria causes severe disease in children

Researchers at Karolinska Institutet in Sweden have discovered that excessive degradation of the power plants of our cells plays an important role in the onset of mitochondrial disease in children.

12 Jun 2020

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

From UC San Diego 12 Jun 2020

Baylor researchers uncover a novel mechanism that triggers cellular immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that specifically recognize parts of the invading microbe and mediate its destruction.

12 Jun 2020

Diversity of plant cell gatekeepers could be key to develop crops with bigger yields

Scientists have shed new light on how the network of gatekeepers that controls the traffic in and out of plant cells works, which researchers believe is key to develop food crops with bigger yields and greater ability to cope with extreme environments.

12 Jun 2020

Lungs' immune cells can be activated more easily than previously thought

A significant site of damage during COVID-19 infection is the lungs. Understanding how the lungs' immune cells are responding to viral infections could help scientists develop a vaccine.

12 Jun 2020

New study may lead to novel treatments for heart and liver diseases

A study that closely analyzed the cardiac health of flies offers new evidence that dysfunction in the liver may result in the deterioration of the heart.

11 Jun 2020

Intron detention is integral to post-transcriptional regulation mechanism

Muscle stem cells are the reserve stem cells found in skeletal muscles. They play a crucial role in muscle repair following damage.

11 Jun 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Stress-induced chemoresistance is linked to changes in cellular metabolism

There is a wide range of mechanisms related to chemoresistance, a majority of which are yet to be fully understood.

11 Jun 2020

'Lab-on-a-chip' technology accurately detects early and advanced breast cancer

A scalable "lab-on-a-chip" technology based on inkjet printing methods detected breast cancer in plasma samples from patients with more than 90% accuracy, according to a new study.

11 Jun 2020

Microneedle depots effectively deliver stem cells into damaged tissues

Mesenchymal stem cells are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues.

10 Jun 2020

Researchers identify genes involved in the development of malignant brain tumor

Researchers have developed a new approach to identify functional mutations and their impact on genes applicable to the development of malignant brain tumors.

10 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Immune system could be 're-trained' to stop attack of healthy cells, study finds

The body's immune system can be re-wired to prevent it from recognizing its own proteins which, when attacked by the body, can cause autoimmune diseases like multiple sclerosis, a significant new study by UK scientists has found.

10 Jun 2020

Cellular mechanophenotyping may help better understand tumor cells

Our ability to predict who will get cancer, how a patient will respond to treatment, or if a patient will relapse is still quite limited. Despite advances in the detection of genetic mutations and the establishment of risk factors, such as age and genetic variants, it remains a great scientific and medical challenge.

10 Jun 2020

KAUST scientists reveal the genetic metronome within malaria parasites

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

Cell Biology

Researchers discover signaling pathway that can regulate beige fat thermogenesis

Cardiac organoids that closely mimic physiological conditions during a heart attack

Human stem cell models reveal neurodegeneration in glaucoma

Researchers create a new model to study early stage of human development

Excessive degradation of mitochondria causes severe disease in children

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Baylor researchers uncover a novel mechanism that triggers cellular immune response

Diversity of plant cell gatekeepers could be key to develop crops with bigger yields

Lungs' immune cells can be activated more easily than previously thought

New study may lead to novel treatments for heart and liver diseases

Intron detention is integral to post-transcriptional regulation mechanism

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

Stress-induced chemoresistance is linked to changes in cellular metabolism

'Lab-on-a-chip' technology accurately detects early and advanced breast cancer

Microneedle depots effectively deliver stem cells into damaged tissues

Researchers identify genes involved in the development of malignant brain tumor

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Immune system could be 're-trained' to stop attack of healthy cells, study finds

Cellular mechanophenotyping may help better understand tumor cells

KAUST scientists reveal the genetic metronome within malaria parasites

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