Cell Biology

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Nanoparticle-Based Therapy Shows Promise in Eradicating Tumors

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.

28 Mar 2024

Autofluorescence Reveals Clues to Stem Cell Dormancy

With the help of a tool created at the University of Wisconsin–Madison, researchers can better study the various states of stem cells in the nervous system by utilizing the light naturally emitted by biological specimens.

28 Mar 2024

Study Sheds Light on Human Neocortex Evolution

Neurobiologists are certain that the neocortex is the defining factor that distinguishes humans.

28 Mar 2024

GPT-4 Streamlines Cell Type Identification in Single-Cell RNA Sequencing

A new study by Columbia University’s Mailman School of Public Health shows that GPT-4, a large language model, can accurately identify cell types in single-cell RNA sequencing data.

26 Mar 2024

New Theory Links Gene Length to Cellular Decline

A gene’s length may have more to do with aging than particular “aging genes.” Reduced expression of long genes may be the cause of many aging-related changes, according to researchers writing an opinion piece that was published in the journal Trends in Genetics on March 21st, 2023.

25 Mar 2024

Unraveling the Mysteries of Brown Algae's Sex Chromosomes

Researchers from the Max Planck Institute for Biology Tübingen made a groundbreaking discovery, revealing that an HMG-box gene in brown algae plays a crucial role in determining male sex.

25 Mar 2024

New Study Unveils Mechanism Behind Mice Ovary Development

Scientists at the Francis Crick Institute have provided insight into the proteins governing the development of mice's ovaries both prenatally and postnatally. This might help comprehend the progression of female infertility.

25 Mar 2024

New Study Sheds Light on Blood-Brain Barrier Dysfunction in Aging

The central nervous system requires a tightly controlled environment for the neurons in the brain to function properly and be able to process information. The blood-brain barrier, which is maintained by specific brain endothelial cells lining blood vessel inner walls, controls the exchange of chemicals between the neurological and circulatory systems.

25 Mar 2024

Research Sheds Light on Blood Cell Production in Mouse Skeleton

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.

25 Mar 2024

Groundbreaking Physics Study Offers Insights Into Self-Organization of Biological Particles

Erin McCarthy '23, physics summa cum laude, is a rarity among young scientists. As an undergraduate researcher in Syracuse University's College of Arts & Sciences' Department of Physics, she guided a study that appeared in March 2024 in Physical Review Letters. It is the most-cited physics letters journal and the eighth-most cited journal in science overall.

25 Mar 2024

Unraveling the Role of Gene Length in Aging

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Bioinformatics Tool Recognizes Chromosome Changes in Cancer Cells

A group from IRB Barcelona and the University of Barcelona has created a novel bioinformatics instrument to recognize the chromosomal changes characteristic of cancerous cells.

22 Mar 2024

New Approach to Constructing Human Artificial Chromosomes Avoids Unintended Multimerization

Constructing human artificial chromosomes (HACs) in budding yeast overcomes the long-standing problem of uncontrolled multimerization – the rampant joining of similar molecules – and results in HACs that are large, stable, and structurally well-defined, researchers report.

22 Mar 2024

Non-Immune Cells Form Memory, Boosts Inflammatory Response

An essential component of adaptive immunity is immunological memory, which is the capacity to react to a foreign material or antigen more quickly and intensely when exposed again.

21 Mar 2024

Decoding the Dynamics of Multiple Sclerosis Lesions

Scientists in Sweden were able to uncover the molecular mechanisms behind the development of lesions in multiple sclerosis by employing sophisticated techniques. The latest findings are detailed in the journal Cell by a team of researchers from Karolinska Institutet and Stockholm University.

21 Mar 2024

Latest CRISPR-Cas Gene Editing Can Eliminate All Traces of HIV Virus From Infected Cells

New research presented early ahead of this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) from a team of researchers in the Netherlands shows how the latest CRISPR-Cas gene editing technology can be used to eliminate all traces of the HIV virus from infected cells in the laboratory, raising hopes of a cure.

20 Mar 2024

Insulin Influences Mitochondrial Recycling in Neurons

The hormone insulin controls many cellular processes and adapts them to the body's current energy supply.

20 Mar 2024

Drug Candidates Show Promise to Reverse HIV's Ability to Escape Immune System Detection

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

20 Mar 2024

The Assemblage of Nuclear Sub-Structures

Researchers from the lab of Rohit Pappu and associates at the Center for Biomolecular Condensates have figured out how nucleolar sub-structures are assembled, a first for the condensate field.

19 Mar 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024