Cell Biology

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Researchers discover unusual exploitation of the human immune system by fungus Candida albicans

During infection, the yeast Candida albicans stimulates the release of tiny RNA fragments, which then stimulate its own growth.

3 Mar 2022

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

SARS-CoV-2 spike protein can specifically recognize the terminal sialic acid on sugars

The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pandemic outbreak in 2019, the ACE-2 protein, which is present on some of our cells´ surface, was identified as the receptor facilitating host cell viral entry.

3 Mar 2022

Innovative sample preparation method for fast and easy protein analysis

In recent years, proteomics research using mass spectrometry to comprehensively investigate the protein components of biological samples has become very popular.

3 Mar 2022

Simple lab model helps investigate the properties of muscle cells from sIBM patients

A team of researchers at Tohoku University have developed a simple lab-based system for growing human muscle cells that are capable of vigorously contracting.

3 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Researchers discover how pancreatic cells remodel themselves to reduce the immune response in patients at risk for T1D

Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.

2 Mar 2022

Researchers design a new imaging approach to accelerate imaging-based research

A new imaging method has been designed and tested by scientists from Johns Hopkins Medicine.

2 Mar 2022

Men and women do have immune cell differences, study says

Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.

2 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

Researchers discover new stem cell population that closely matches existing human stem cells

Reik lab researchers’ recent discovery describes a new subpopulation of human embryonic stem cells that closely match the cells present at the genomic “wake up call” of the 8-cell embryo stage in humans.

28 Feb 2022

Macrophages restore normal functions when transported back to the body, says research

New research shows that some immune cells could reinstate their regular functions when they are introduced back into the body.

28 Feb 2022

Study investigates the relationship between healthy tissue repair and cancer growth

Scientists at the Francis Crick Institute have revealed how a mechanism involved in the regeneration of tissue can help the spread of cancer.

28 Feb 2022

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the uncontrolled growth of cancer cells.

25 Feb 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Researchers gain better understanding of the fast signaling dynamics in stem cells

Divide, differentiate or die? Making decisions at the right time and place is what defines a cell's behavior and is particularly critical for stem cells of an developing organisms.

From The Max Planck Institute 25 Feb 2022

Single Use Support brings cell & gene therapy expert Katy Spink on board

Katherine (Katy) Spink has become a member of Single Use Support’s Board of Directors. Her many years of expertise in cell & gene therapy consulting will enrich the companies’ focus on innovating solutions for advanced therapies.

From Single Use Support GmbH 25 Feb 2022

Cell Biology

Researchers discover unusual exploitation of the human immune system by fungus Candida albicans

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

SARS-CoV-2 spike protein can specifically recognize the terminal sialic acid on sugars

Innovative sample preparation method for fast and easy protein analysis

Simple lab model helps investigate the properties of muscle cells from sIBM patients

Protein appears key to the function and survival of brain cells most impacted by glaucoma

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Researchers discover how pancreatic cells remodel themselves to reduce the immune response in patients at risk for T1D

Researchers design a new imaging approach to accelerate imaging-based research

Men and women do have immune cell differences, study says

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

US research reveals the role of Heparan Sulfate in obesity

Looking at protein activity gives a complete picture of leukemia's weaknesses

Researchers discover new stem cell population that closely matches existing human stem cells

Macrophages restore normal functions when transported back to the body, says research

Study investigates the relationship between healthy tissue repair and cancer growth

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Researchers create a regulatory map of zebrafish genome

Researchers gain better understanding of the fast signaling dynamics in stem cells

Single Use Support brings cell & gene therapy expert Katy Spink on board

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