Drug Discovery & Pharmaceuticals

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Emerging hydrogel material could improve delivery of oral drugs

An emerging hydrogel material with the capacity to degrade and spontaneously reform in the gastrointestinal tract could help researchers develop more effective methods for oral drug delivery.

From Lehigh University 20 Jul 2020

Beautyberry leaf extract boosts drug's activity antibiotic-resistant staph bacteria

Scientists discovered a compound in the leaves of a common shrub, the American beautyberry, that boosts an antibiotic's activity against antibiotic-resistant staph bacteria. Laboratory experiments showed that the plant compound works in combination with oxacillin to knock down the resistance to the drug of methicillin-resistant Staphylococcus aureus, or MRSA.

17 Jul 2020

Changes in glioblastoma cells influence the effect of different drugs, shows study

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

15 Jul 2020

Study suggests ways to improve antibiotic allergy registrations

Antibiotics are among the most commonly prescribed medications, but in determining the most appropriate prescription for a patient, doctors and pharmacists often rely on inaccurate records of the patient's antibiotic allergies.

15 Jul 2020

Innovative robot can help develop medicated chewing gum

Medicated chewing gum has been recognised as a new advanced drug delivery method but currently there is no gold standard for testing drug release from chewing gum in vitro.

15 Jul 2020

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

UTMB researchers uncover new mechanism for designing dengue therapeutics

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

Researchers discover promising drug candidate for treatment of brain disorders

Researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) discovered a novel chemical compound, which has the potential to became a new drug for the treatment of core symptoms of brain disorders like Down syndrome and autism.

13 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

New start-up to exploit novel drug-transporting technology

Researchers from IRB Barcelona, the University of Barcelona (UB) and the Sant Joan de Déu Research Institute - Hospital Sant Joan de Déu (SJD) have set up Gate2Brain, a company based on a novel technology developed at IRB Barcelona to transport drugs into the brain.

10 Jul 2020

New device can help test potential drug candidates for COVID-19

Scientists have created a human cell “membrane on a chip” that enables tracking of the interaction of drugs and infectious agents with the human cells.

6 Jul 2020

Researchers identify protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

6 Jul 2020

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

3 Jul 2020

UTEP researchers discover new target for tuberculosis drug development

Biology students and faculty members from The University of Texas at El Paso have discovered a new target for tuberculosis drug development.

1 Jul 2020

In vitro cardiotoxicity screening using 3D-printed human heart tissues

Ramot at Tel Aviv University has signed a collaboration agreement with Bayer to develop and validate a platform for in vitro cardiotoxicity screening, using human heart tissues 3D-printed in Prof. Tal Dvir's Laboratory for Tissue Engineering and Regenerative Medicine at Tel Aviv University.

1 Jul 2020

Chiral ligands can help develop novel drugs and bioactive compounds

Numerous therapeutic compounds—such as amino acids, enzymes, and proteins— that are currently available in the market are “chiral compounds.”

1 Jul 2020

Sanford Burnham Prebys announces research agreement with Lilly to characterize COVID-19 antibodies

Sanford Burnham Prebys Medical Discovery Institute today announced a research agreement with Eli Lilly and Company (Lilly) to characterize Lilly's next-generation anti-SARS-CoV-2 antibodies.

30 Jun 2020

Drug Discovery & Pharmaceuticals

Emerging hydrogel material could improve delivery of oral drugs

Beautyberry leaf extract boosts drug's activity antibiotic-resistant staph bacteria

Changes in glioblastoma cells influence the effect of different drugs, shows study

Study suggests ways to improve antibiotic allergy registrations

Innovative robot can help develop medicated chewing gum

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

UTMB researchers uncover new mechanism for designing dengue therapeutics

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Researchers discover promising drug candidate for treatment of brain disorders

New drug enables the immune system to attack ovarian cancer, TGen study shows

New start-up to exploit novel drug-transporting technology

New device can help test potential drug candidates for COVID-19

Researchers identify protective antibodies for rare, polio-like disease in children

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

UTEP researchers discover new target for tuberculosis drug development

In vitro cardiotoxicity screening using 3D-printed human heart tissues

Chiral ligands can help develop novel drugs and bioactive compounds

Sanford Burnham Prebys announces research agreement with Lilly to characterize COVID-19 antibodies

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