Genomics

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Researchers identify a new gene to treat multiple sclerosis

Multiple sclerosis, or MS, is a disease that affects the central nervous system and can eventually lead to muscle tremors and thus loss of balance.

17 Aug 2020

Study sheds light on genetic and molecular mechanisms involved in atopic dermatitis

The KIF3A gene contains common variants that raise the risk of a dysfunctional skin barrier and ultimately lead to a skin condition, called atopic dermatitis.

17 Aug 2020

NIH-supported research delineates how genetic variations cause atopic dermatitis

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.

17 Aug 2020

Flavonoids in sorghum roots may lead to development of frost-resistant crop

Flavonoid compounds -- produced by the roots of some sorghum plants -- positively affect soil microorganisms, according to Penn State researchers, who suggest the discovery is an early step in developing a frost-resistant line of the valuable crop for North American farmers.

14 Aug 2020

Scientists shed new light on the evolution and function of shapes seen in nature

Researchers have shed fresh light on the evolution and function of the shapes we see in nature - using as a model the heart shaped fruits of the Capsella genus.

14 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Triple-negative breast cancer's ecosystem reveals potential therapeutic targets

Researchers from the Garvan Institute of Medical Research have uncovered four new subtypes of cells within triple-negative breast cancer, which contain promising new therapeutic targets for the aggressive disease.

13 Aug 2020

Genetic analysis could be used to counsel parents after stillbirth

Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the condition's genetic foundations.

13 Aug 2020

HPV type may impact characteristics and prognosis of cervical cancer

An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumors caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics and prognosis.

11 Aug 2020

Study shows human genome regulates the early development of organs

A team of researchers has identified how the human genome regulates the development of several organs that are crucial to human life.

From The University of Manchester 11 Aug 2020

Adaptive parallel mutations are more common in Lake Baikal amphipods

A group of scientists from Skoltech and the Institute for Information Transmission Problems of RAS (IITP RAS) showed, using Lake Baikal amphipods as an example, that parallel evolution driven by adaptations can be detected at the whole-genome level.

11 Aug 2020

A genetic switch in brain cells can toggle between sex-specific states when necessary

Biological sex is typically understood in binary terms: male and female. However, there are many examples of animals that are able to modify sex-typical biological and behavioral features and even change sex.

11 Aug 2020

Using genetic engineering to study evolutionary assimilation of foreign DNA in a new host

All life is subject to evolution in the form of mutations that change the DNA sequence of an organism's offspring, after which natural selection allows the 'fittest' mutants to survive and pass on their genes to future generations.

11 Aug 2020

Researchers use genome editing to facilitate drug discovery based on natural fungus

Rice University scientists have won federal support for their pursuit of novel drugs to treat human disease.

11 Aug 2020

Researchers describe a previously unknown phylum of aquatic Archaea

In a publication in Nature Communications last Friday, NIOZ scientists Nina Dombrowski and Anja Spang and their collaboration partners describe a previously unknown phylum of aquatic Archaea that are likely dependent on partner organisms for growth while potentially being able to conserve some energy by fermentation.

11 Aug 2020

$1.2 million NIH grant awarded to create humanized mice susceptible to COVID-19

The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at the University of California, Davis, to create mice that are susceptible to the COVID-19 virus, and to distribute them to researchers.

11 Aug 2020

Gene therapy to the inner retina prevents blindness in Cln3-deficient mice

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease.

11 Aug 2020

Study may reduce transmissible cancer in Tasmanian devils, offers hope for treating human cancers

A rare, transmissible tumor has brought the iconic Tasmanian devil to the brink of extinction, but new research by scientists at Washington State University and the Fred Hutchinson Cancer Research Center in Seattle indicates hope for the animals' survival and possibly new treatment for human cancers.

10 Aug 2020

Increased blood lead levels in children are linked to reduced expression of genes

Researchers have revealed a connection between methylation of genes implicated in heme synthesis and carcinogenesis and high blood lead levels in children, signifying a previously unfamiliar mechanism for lead poisoning.

10 Aug 2020

Study shows how DNA from ancient ancestors was passed down to modern humans

According to a new study of ancient genomes, different branches of the human family tree could have interbred numerous times, and certain human beings carry DNA from an unfamiliar and ancient ancestor.

7 Aug 2020

Genomics

Researchers identify a new gene to treat multiple sclerosis

Study sheds light on genetic and molecular mechanisms involved in atopic dermatitis

NIH-supported research delineates how genetic variations cause atopic dermatitis

Flavonoids in sorghum roots may lead to development of frost-resistant crop

Scientists shed new light on the evolution and function of shapes seen in nature

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

Triple-negative breast cancer's ecosystem reveals potential therapeutic targets

Genetic analysis could be used to counsel parents after stillbirth

HPV type may impact characteristics and prognosis of cervical cancer

Study shows human genome regulates the early development of organs

Adaptive parallel mutations are more common in Lake Baikal amphipods

A genetic switch in brain cells can toggle between sex-specific states when necessary

Using genetic engineering to study evolutionary assimilation of foreign DNA in a new host

Researchers use genome editing to facilitate drug discovery based on natural fungus

Researchers describe a previously unknown phylum of aquatic Archaea

$1.2 million NIH grant awarded to create humanized mice susceptible to COVID-19

Gene therapy to the inner retina prevents blindness in Cln3-deficient mice

Study may reduce transmissible cancer in Tasmanian devils, offers hope for treating human cancers

Increased blood lead levels in children are linked to reduced expression of genes

Study shows how DNA from ancient ancestors was passed down to modern humans

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