Genomics

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Novel method maps all gene expression patterns to a single reference embryo

Years of work by Trinity College Dublin developmental biologists in collaboration with colleagues at the University of Edinburgh’s MRC Human Genetics Unit has resulted in an unparalleled resource that will help researchers assess how key genes control the differentiation of tissues and organs in developing embryos.

23 Aug 2022

Researchers discover a genome that provides an understanding of diterpenoids

Salvia officinalis (S. officinalis), known as sage or common sage, and the Chinese sage (S. miltiorrhiza), or Danshen (red sage) in Chines, pertain to the Lamiaceae family and have been grown for medicinal purposes for a long time in Europe and East Asia, respectively.

22 Aug 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022

New technique reveals how environmental changes affect the dynamic structures of RNAs in living cells

The impact of environmental conditions on the dynamic structures of RNAs in living cells has been revealed by innovative technology developed by researchers at the John Innes Centre.

18 Aug 2022

Liberibacter species closely related to deadly citrus greening disease mutating rapidly

A bacterial species closely related to deadly citrus greening disease is rapidly evolving its ability to infect insect hosts, and possibly plants as well.

16 Aug 2022

Parents transmit genetic and epigenetic information to their offspring

The knowledge of what can be inherited from parents and how their life experiences impact children could be completely rewritten if a fundamental finding concerning a factor driving healthy development in embryos were made.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 15 Aug 2022

Researchers modify the root structure of plants with synthetic genes

Crops need to be more adaptable than ever as extreme weather events like floods, droughts, and heat waves grow more frequently.

15 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Genetic mapping helps to analyze how cancer cells grow

Acknowledging which cells lend credence to which regions of cancer can help us better understand how a tumor has expanded and developed over time, such as how it has altered genetically.

12 Aug 2022

Self‑pollinating flowering plant quickly loses genetic variation without bumble bees

Without bumble bees, a flowering plant that can self-pollinate lost substantial genetic variation within only nine generations, an experimental study found.

11 Aug 2022

Researchers discover antibiotic resistance genes in M. tuberculosis

More than 10,000 different Mycobacterium tuberculosis bacteria isolated from 23 different countries were subjected to a thorough investigation, which uncovered new genes linked to resistance to 13 first- and second-line novel and repurposed medicines.

11 Aug 2022

Study provides guidelines on how to design safer CRISPR reagents

The 2020 Nobel Prize in Chemistry was awarded to Jennifer A. Doudna and Emmanuelle Charpentier for developing the widely utilized and incredibly precise genome editing method known as CRISPR/Cas9

11 Aug 2022

AI tools forecast DNA’s regulatory region and 3D structure

According to two recent research published in Nature Genetics, recently created artificial intelligence (AI) tools effectively identified the function of DNA’s regulatory regions and three-dimensional (3D) structure based only on its raw sequence.

9 Aug 2022

Common weed holds important clues to create drought-resistant crops

A common weed harbors important clues about how to create drought-resistant crops in a world beset by climate change.

9 Aug 2022

Researchers construct large evolutionary trees of marine microbial eukaryotes

A study published recently in the prestigious journal Nature Ecology and Evolution has unveiled some of the key processes in marine microbial evolution.

8 Aug 2022

Study discovers a molecular mechanism that confers special physical properties to chromosomes in dividing human cells

The Gerlich Group at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) has identified a molecular process that gives chromosomes in dividing human cells unique physical characteristics that permit faithful transmission to the progeny.

8 Aug 2022

Researchers make significant improvements to PubCaseFinder, the clinical decision support system

Even medical professionals with years of experience can spend hours researching potential illnesses in reliable medical sources (such as databases, books, and literature) to identify which diseases have phenotypic traits overlapping with the phenotypes of undiagnosed patients.

8 Aug 2022