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Study Identifies Link Between Gut Microbiome Composition and Autism Spectrum Disorder

Autism Spectrum Disorder (ASD), a neurodevelopmental condition characterized by decreased social communication and repetitive behaviors, has long intrigued scientists seeking to unravel its underlying mechanisms.

14 Feb 2024

ReSisTrace: Unveiling Pre-Existing Treatment Resistance in Cancer Cells

In many cancers, such as ovarian cancer, each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment.

14 Feb 2024

New DNA Methylation-Based Analysis Provides Accurate Assessment of Pancreas Cell Composition

Research introduces new DNA methylation-based method for accurately assessing cell composition in the human pancreas, addressing a critical gap in diabetes research.

7 Feb 2024

Study Suggests a Link Between DNA Methylation Disorder and Epigenetic Clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation."

7 Feb 2024

Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

2 Feb 2024

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Protein degraders, a novel approach in drug discovery, show promise to tackle diseases previously thought to be untreatable.

31 Jan 2024

Gene Therapy Can Interrupt the Progression of Deadly Inherited Heart Condition

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

31 Jan 2024

Scientists Unleash the Power of Calcium to Target and Destroy Tumor Cells

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

Study Shows How Obesity Causes Mitochondrial Fragmentation in Fat Cells

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic.

30 Jan 2024

Traffic Jam in the Brain: Study Uncovers Cellular Cause of Rare Neurological Disease

Researchers from McGill University, led by Professor Alanna Watt of the Department of Biology, have identified previously unknown changes in brain cells affected by a neurological disease.

22 Jan 2024

Understanding How Inherited DNA Variations Influence Blood Cancer Development

Large-scale genetic analysis has helped researchers uncover the interplay between cancer-driving genetic mutations and inherited genetic variants in a rare type of blood cancer.

18 Jan 2024

Genome-Wide Study Identifies Gene Pair Crucial for Regulating Blood Vessel Disease in the Lungs

University of Pittsburgh Schools of Medicine researchers uncovered a fundamental mechanism that controls the body's response to limited oxygen and regulates blood vessel disease of the lung.

16 Jan 2024

Mosaic Turner Syndrome Identified in 2500-Year-Old Briton: Ancient DNA Reveals Hidden History

Researchers at the Francis Crick Institute, working with University of Oxford, University of York and Oxford Archaeology, have developed a new technique to measure the number of chromosomes in ancient genomes more precisely, using it to identify the first prehistoric person with mosaic Turner syndrome (characterized by one X chromosome instead of two [XX]), who lived about 2500 years ago.

16 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024

EBV-Targeting T-Cells Linked to Early MS Damage

The body's immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multiple sclerosis, according to a new study led by UTHealth Houston.

12 Jan 2024

Boosting Post-Transplant Survival: Tailoring Gut Microbiome to Fight GvHD

After stem cell transplantation, the donated immune cells sometimes attack the patients' bodies. This is known as graft versus host disease or GvHD.

9 Jan 2024

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Amino acids, such as tyrosine and tryptophan, are the fundamental building blocks that make up proteins.

9 Jan 2024

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

5 Jan 2024

Genetic Twist in Tiny Protein Protects Against Parkinson's

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

3 Jan 2024

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

3 Jan 2024

Medical Condition News

Study Identifies Link Between Gut Microbiome Composition and Autism Spectrum Disorder

ReSisTrace: Unveiling Pre-Existing Treatment Resistance in Cancer Cells

New DNA Methylation-Based Analysis Provides Accurate Assessment of Pancreas Cell Composition

Study Suggests a Link Between DNA Methylation Disorder and Epigenetic Clocks

Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Gene Therapy Can Interrupt the Progression of Deadly Inherited Heart Condition

Scientists Unleash the Power of Calcium to Target and Destroy Tumor Cells

Study Shows How Obesity Causes Mitochondrial Fragmentation in Fat Cells

Traffic Jam in the Brain: Study Uncovers Cellular Cause of Rare Neurological Disease

Understanding How Inherited DNA Variations Influence Blood Cancer Development

Genome-Wide Study Identifies Gene Pair Crucial for Regulating Blood Vessel Disease in the Lungs

Mosaic Turner Syndrome Identified in 2500-Year-Old Briton: Ancient DNA Reveals Hidden History

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

EBV-Targeting T-Cells Linked to Early MS Damage

Boosting Post-Transplant Survival: Tailoring Gut Microbiome to Fight GvHD

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

Genetic Twist in Tiny Protein Protects Against Parkinson's

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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