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New technique may offer a pathway to treat undruggable diseases

Certain diseases, including Alzheimer's, are currently considered "undruggable" because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses.

2 Mar 2023

New model, C. elegans, helps pursue research on Parkinson's disease

A tiny worm called the C. elegans is enabling scientists to explore the emerging theory that Parkinson's disease starts in the gut.

1 Mar 2023

RNA modification plays a vital role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis-the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease-involve the buildup of a protein called TDP-43.

28 Feb 2023

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

28 Feb 2023

The relationship between cancer and DMD gene expression discovered

Mutations of the gene encoding dystrophins have long been known to cause the debilitating muscle-wasting disease DMD, which affects one in every 5,000 boys born. People with the condition will usually only live into their 20s or 30s.

28 Feb 2023

Redefining low-risk WNT-pathway medulloblastoma based on newer biological information

A new research perspective was published in Oncotarget's Volume 14 on February 7, 2023, entitled, "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"

28 Feb 2023

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

A tumor's necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.

28 Feb 2023

Study highlights key role of group 2 innate lymphoid cells in shaping the alveolar niche

A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react differently to exposure to certain respiratory allergens.

27 Feb 2023

New molecular understanding of how head injury may contribute to glioma risk

Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.

27 Feb 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

Genes can be used to better predict the likelihood of kidney cancer recurrence

A decade-long international study into kidney cancer has shown that doctors can predict the likelihood of a patient's disease returning by looking at DNA mutations in their tumors.

24 Feb 2023

Researchers tease apart the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

24 Feb 2023

Discovery of a lung stem cell subset provides opportunity for new COPD treatments

Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one of the most common diagnoses for hospital admissions.

24 Feb 2023

Medical Condition News

New technique may offer a pathway to treat undruggable diseases

New model, C. elegans, helps pursue research on Parkinson's disease

RNA modification plays a vital role in TDP-43-related neurodegeneration in ALS

Cell therapy trial promises long-term improvement for patients with chronic heart failure

The relationship between cancer and DMD gene expression discovered

Redefining low-risk WNT-pathway medulloblastoma based on newer biological information

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

Study highlights key role of group 2 innate lymphoid cells in shaping the alveolar niche

New molecular understanding of how head injury may contribute to glioma risk

Study shows why a specific gene mutation has opposite effects on mice and human cancers

Genes can be used to better predict the likelihood of kidney cancer recurrence

Researchers tease apart the molecular components involved in abdominal aneurysms

Discovery of a lung stem cell subset provides opportunity for new COPD treatments

Scientists discover two ways to preserve diseased upper motor neurons in ALS

Study provides new insight into the brain circuits involved in opioid addiction

UTA professor leads a state-funded project to explore how T-cells detect cancer

Mount Sinai researchers reveal mechanisms underlying autoimmunity in Down syndrome

Modifying patients' intestinal flora could be a new therapeutic approach for colon cancer

Mount Sinai researchers illuminate the role of DNA methylation in Alzheimer's disease

Monitoring bovine meat and milk factor protein expression could enable colorectal cancer detection

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