Medical Condition News

RSS

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

New research published in the Proceedings of the National Academy of Sciences shows that examining genetic mutations in individuals with severe schizophrenia can improve the ability to detect disease-associated rare genetic variants.

15 Dec 2021

Study provides new insight into the genetics of severe schizophrenia

Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.

14 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

13 Dec 2021

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

8 Dec 2021

Long-term exposure to particulate matter associated with hypertension

According to the WHO, air pollution is the greatest health risk worldwide, accounting for more than 4.2 million deaths annually.

6 Dec 2021

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

In the late 1980s, scientists developed a revolutionary approach to treating acute myeloid leukemia (AML), a type of blood cancer. Called differentiation therapy, it amounted to a bona fide cure for many patients.

2 Dec 2021

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

1 Dec 2021

Researchers show that tumor cells contribute differently to the formation of metastases

A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere.

30 Nov 2021

Researchers discover a link between genetic variant and chronic hypersensitivity pneumonitis

Chronic hypersensitivity pneumonitis (CHP) is a long-term lung condition where the interstitial tissue surrounding the alveoli (air sacs) of the lungs becomes inflamed and develops "fibrosis", or scar tissue.

17 Nov 2021

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases.

11 Nov 2021

Immune system–related differences in dialysis, kidney transplant patients are amplified by SARS-CoV-2

People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19.

8 Nov 2021

Multiple sclerosis drug improves memory in mouse model of Alzheimer's disease

Losing memory is a hallmark of Alzheimer's, a symptom of the disease that depletes a patient's quality of life. Improving memory and slowing cognitive changes caused by the disease is an ongoing challenge for researchers seeking to develop novel therapies.

8 Nov 2021

Peanut consumption associated with reduced risk of ischemic stroke in Asian population

Asian men and women living in Japan who ate peanuts (on average 4-5 peanuts/day) had a lower risk of having an ischemic stroke or a cardiovascular disease event compared to those who did not eat peanuts, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

9 Sep 2021

Recent cannabis use associated with myocardial infarction in young adults

Adults younger than 45 years who reported recently using cannabis were 2 times more likely to have had a heart attack (myocardial infarction), and this link was stronger in frequent users, according to new research in CMAJ.

From University of Toronto 9 Sep 2021

Medical Condition News

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

Study provides new insight into the genetics of severe schizophrenia

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

Long-term exposure to particulate matter associated with hypertension

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Researchers show that tumor cells contribute differently to the formation of metastases

Researchers discover a link between genetic variant and chronic hypersensitivity pneumonitis

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Immune system–related differences in dialysis, kidney transplant patients are amplified by SARS-CoV-2

Multiple sclerosis drug improves memory in mouse model of Alzheimer's disease

Peanut consumption associated with reduced risk of ischemic stroke in Asian population

Recent cannabis use associated with myocardial infarction in young adults

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics