Microbiology

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UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

Revealing the structural basis underpinning the biophysical properties of pili

According to the World Health Organization, enterotoxigenic Escherichia coli (ETEC) bacteria are the most common cause of traveler’s diarrhea and cause the greatest number of known community-acquired cases of childhood diarrhea in the developing world.

31 Mar 2023

Maternal vaginal microbiome does not substantially influence the infant stool microbiome

It has been a longstanding assumption that birth mode and associated exposure of newborns to their mothers' vaginal microbiome during delivery greatly affects the development of babies' gut microbiome.

31 Mar 2023

Research shows how the fruit fly gut builds a cozy niche to selectively promote colonization

The digestive tract of fruit flies remodels itself to accommodate beneficial microbiome species and maintain long-term stability of the gut environment, according to new research led by Carnegie's William Ludington and Allan Spradling.

30 Mar 2023

Study reports a new target to fight against antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

30 Mar 2023

Novel inhibitor, hopeaphenol, blocks HIV expression

In the United States, around 1.2 million people are living with HIV as of 2022. Many of these people can now live productive, symptom-free lives thanks to antiretroviral therapies, but a solution that permanently removes HIV from an infected person’s body is still a long way off.

30 Mar 2023

Using better probiotics to maintain a healthy gut microbiome

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

29 Mar 2023

New DNA editing tool could rapidly accelerate the design of custom microbes

A DNA editing tool adapted by Oak Ridge National Laboratory scientists makes engineering microbes for everything from bioenergy production to plastics recycling easier and faster.

29 Mar 2023

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

A University of Massachusetts Amherst nutrition scientist who has spent his career studying breast milk has demonstrated how beneficial microbes in the gut of infants use nitrogen from human milk to support pediatric nutrition and development.

28 Mar 2023

Resistance genes in human gut influenced by national trends in antibiotic consumption

According to a new study performed at the Earlham Institute and Quadram Institute in Norwich, the community of microbes living in and on human bodies might be serving as a reservoir for antibiotic resistance.

28 Mar 2023

Investigating methanogens to unravel the genetics of temperature adaptation

The history of the Earth has been one of physical extremes-;extreme atmospheric conditions, extreme chemical environments, and extreme temperatures.

28 Mar 2023

Scientists develop a detailed "protein atlas" of a pathogen for the first time

A parasite which has devasting impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells – providing clues to their function and helping to identify potential drug targets.

27 Mar 2023

Meta-scale approach to quantifying the protein variants in the human body

A key conundrum in biology is why many very simple creatures, such as the widely studied worm C. elegans, have almost as many genes as the human genome, which has about 20,000 genes.

27 Mar 2023

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

The removal of obsolete and damaged cell components by the body is crucial for fighting diseases like tuberculosis (TB), which establish themselves inside human cells, according to researchers from the Francis Crick Institute.

27 Mar 2023

Global warming could increase the number and spread of fatal bacterial infections

Continued warming of the climate would see a rise in the number and spread of potentially fatal infections caused by bacteria found along parts of the coast of the United States.

24 Mar 2023

Effective encoding strategy streamlines the handling and storage of single-cell data

Single-cell analysis is an effective biomedical technique used to identify unusual cell populations, monitor cell development and differentiation, comprehend disease causes, and design individualized therapies, but it generates massive amounts of data that can be challenging to handle.

23 Mar 2023

Microbiology

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Revealing the structural basis underpinning the biophysical properties of pili

Maternal vaginal microbiome does not substantially influence the infant stool microbiome

Research shows how the fruit fly gut builds a cozy niche to selectively promote colonization

Study reports a new target to fight against antibiotic-resistant pneumonia

Novel inhibitor, hopeaphenol, blocks HIV expression

Using better probiotics to maintain a healthy gut microbiome

New DNA editing tool could rapidly accelerate the design of custom microbes

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

Resistance genes in human gut influenced by national trends in antibiotic consumption

Investigating methanogens to unravel the genetics of temperature adaptation

Scientists develop a detailed "protein atlas" of a pathogen for the first time

Meta-scale approach to quantifying the protein variants in the human body

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

Global warming could increase the number and spread of fatal bacterial infections

Effective encoding strategy streamlines the handling and storage of single-cell data

Identifying biomarkers that help treat fatty liver patients with a personalized diet

Using viruses to fight antibiotic-resistant "superbugs"

CABBI/GLBRC researchers peer into the complexities of life on a leaf

Stickiness of influenza virus may determine the frequency of co-infection

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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