Proteomics

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Researchers reveal identity of the last unknown protein of autophagy

Drs. Nobuo Noda (Director) and Kazuaki Matoba (Senior Researcher) et al. at the Institute of Microbial Chemistry (BIKAKEN, Tokyo, Japan) discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) between the two layers of the lipid bilayer and elucidated that the protein's activity brings about autophagosome membrane expansion.

5 Nov 2020

Researchers unlock new possibilities for development of sustainable, clean bioenergy

Researchers at the University of Liverpool have unlocked new possibilities for the future development of sustainable, clean bioenergy.

4 Nov 2020

Study reveals proteins that enable SINEUPs to increase protein production

Scientists from an international group led by the RIKEN Center for Integrative Medical Sciences and Yokohama City University have discovered that a pair of proteins play a key role in allowing an important type of functional non-coding RNA, known as SINEUPs, to act to promote their target messenger RNA.

2 Nov 2020

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease.

29 Oct 2020

Simple skin test can accurately identify Parkinson's disease

New research shows a simple skin test can accurately identify Parkinson's disease, demonstrating for the first time the feasibility of the method. Currently diagnosed by clinical signs and symptoms but only definitively diagnosed at autopsy, Parkinson's disease is commonly misdiagnosed early in the disease course, complicating clinical trials of potential treatments.

22 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

First-ever draft sequence of the human proteome mapped successfully

Two decades after the release of the human genome, researchers have mapped the first-ever draft sequence of the human proteome.

21 Oct 2020

A new look at an old technique for studying protein dynamics

A fresh new look at an old technique in protein biochemistry has shown that it should be reintroduced to the spectroscopy toolkit.

20 Oct 2020

Bioinformatics expert to design antibody-antigen interface to predict peptide sequences

Dmitri Klimov, Professor, Bioinformatics and Computational Biology, is creating a computational platform for designing an antibody-antigen interface based on DNA origami.

19 Oct 2020

A new protein discovered that repairs DNA

Researchers have identified a new protein that makes it possible to repair DNA. The protein in question is called cryptochrome.

15 Oct 2020

Two proteins compete to give shape to plants

In an elegant choreography, plants take cues from their environment and channel them into flowers, roots, or branches.

13 Oct 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

New index relies on pigs to demonstrate protein quality for humans

Nearly a decade ago, the UN's Food and Agriculture Organization (FAO) developed a new index to assess protein quality in foods. The goal, writ large, was to address food security for the world's most vulnerable populations, creating more accurate tools for food assistance programs seeking to provide balanced nutrition.

24 Sep 2020

Making healthy, environmentally friendly protein from the air

Increasing environmental challenges have led scientists to rethink how protein can be produced. Traditional processes require a lot of space on land or sea, resulting in a high carbon footprint and reduced resources.

24 Sep 2020

Researchers create an algorithm that predicts allosteric sites in proteins

A new technology that uses a protein's structure to predict the inner wiring that controls the protein's function and dynamics is now available for scientists to utilize.

4 Sep 2020

Study shows how high-protein diet protects against fatty liver

Non-alcoholic fatty liver disease is the most common chronic liver disease in the world, with sometimes life-threatening consequences.

19 Aug 2020

Protective anti-prion antibodies found in humans

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies.

18 Aug 2020

Scientists discover bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

18 Aug 2020

Protein produced by nervous system may be the key to treating inflammatory diseases

A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

From Rutgers University 18 Aug 2020

Study identifies a protein that facilitates spread of SARS-CoV-2 virus through cells

Eric Ross and Sean Cascarina, biochemistry and molecular biology researchers at Colorado State University, have released a research paper identifying a protein encoded by SARS-CoV-2, the virus that causes COVID-19, that may be associated with the quick spread of the virus through cells in the human body.

13 Aug 2020