Proteomics

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Breakthrough mRNA Technology Paves the Way for Precision Medicine

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

20 Feb 2025

Researchers Discover New Role of Mitofusin 2 in Cellular Health

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

17 Feb 2025

PanK4 Protein Could Be Key to Better Control of Blood Sugar and Metabolism

Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr. Maximilian Kleinert at the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE). His team discovered that the protein PanK4 plays a crucial role in the energy metabolism of skeletal muscles.

13 Feb 2025

Exploring Chromatin's Resilience to Develop Anti-Aging Strategies

The process of aging in the body may be more resilient than previously believed, according to a new study.

4 Feb 2025

Durham University Researchers Unveil Tool to Predict Protein Metalation

Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life.

30 Jan 2025

New Numbering System Advances Adhesion GPCR Research

Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies.

29 Jan 2025

Fast and Precise Protein Labeling in Intact Tissues with MIT Technology

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility.

27 Jan 2025

New Breakthrough Pushes DNA-Nanoparticle Motors Closer to Natural Protein Speed

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation.

23 Jan 2025

AI-Powered Platform for Designing Novel Protein Interactions

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for biomedicine by using deep learning to create new proteins that bind to complexes involving other small molecules, such as hormones or medications.

17 Jan 2025

Protein Shapes Reveal Deeper Evolutionary Relationships

According to a study published in the journal Nature Communications, the three-dimensional form of a protein can be utilized to determine long-standing evolutionary relationships in the tree of life.

16 Jan 2025

Researchers Discover How Protein Instability Drives Heritable Diseases

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature.

10 Jan 2025

UK Biobank to Study Protein Changes Across 600,000 Samples

UK Biobank has today announced the launch of the world's most comprehensive study of the proteins circulating in our bodies, which will transform the study of diseases and their treatments.

10 Jan 2025

Arabidopsis Study Finds that Centromeres Call the Shots in Retrotransposon Integration

Centromeres play a crucial role in cell division, with CENH3 guiding retrotransposon Tal1 integration, revealing insights into genome evolution and stability.

10 Jan 2025

Rewriting History: Advanced Genetic Analysis Uncovers Ancient Ancestry Shifts in Europe

High-resolution analysis of ancient genomes reveals key Scandinavian ancestry movements in early medieval Europe, highlighting complex genetic interactions.

9 Jan 2025

New Sequencing Method Unveils Adaptive States and Host-Phage Interactions in the Gut

The human gut microbiome is complex and diverse, with significant implications for health and disease. The study develops smRandom-seq2, a droplet-based method that overcomes the limitations of existing techniques by capturing RNA from a wide variety of species.

2 Jan 2025

New HG-TCs Strategy Enables Efficient Analysis of Glycosylation in Cells

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

27 Dec 2024

New Platform Simplifies Protein-Protein Interaction Measurements

A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy.

26 Dec 2024

Chaperone Proteins Unveil Their Role in Neurotransmission

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating diseases such as Alzheimer's and Parkinson's along with many others, can occur.

19 Dec 2024

New Method Revolutionizes Protein Analysis for Diverse Populations

With a new method developed at the University of Bergen, researchers can now refine the analysis of proteins taking into account population diversity.

10 Dec 2024