Proteomics

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Study Reveals Dual Role of Skin Proteins in Strength and Cell Signaling

An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows.

22 Aug 2024

New AI Tool Predicts Protein Behavior in Cellular Context

A fish on land can still wave its fins, but the outcomes are very different when the creature is in water. The comparison, attributed to prominent computer scientist Alan Kay, is used to demonstrate the importance of context in clarifying research issues.

19 Aug 2024

Harnessing Proteomics to Explore the Role of Probiotic Bacteria in Human Health

The currently available proteomics strategies can be used to identify and quantify probiotic bacterial proteins.

19 Aug 2024

Advancing Cardiovascular Drug Discovery: Translational Framework Leverages Genetic and Proteomic Insights

A validated framework to translate these recent advances in genoproteomics into clinical applications in cardiovascular drug development.

19 Aug 2024

Study Uncovers Biomarkers for Low Muscle Mass, Offering Insights for Personalized Prevention

Machine learning models to analyze computed tomography (CT) images of the chest and a proteomics approach to determine blood protein biomarkers.

15 Aug 2024

Novel Technique to Study Ubiquitination

Once human proteins are synthesized, they go through some chemical changes. These adjustments control their stability, functionality, and structure.

13 Aug 2024

New AI Model Predicts Protein-DNA Binding Specificity with High Accuracy

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

12 Aug 2024

New ProDOL Technique Revolutionizes Protein Counting in Living Cells

Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

12 Aug 2024

UCL Scientists Uncover New Role of Ribosomes in Protein Folding

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.

8 Aug 2024

The Role of Chemical Proteomics in Understanding Small Molecule-Protein Interactions

The various chemical proteomics methods with relevant examples.

31 Jul 2024

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

The niche areas in which phenotypic screening continues to be advantageous over the targeted approach, and the recent advances in phenotypic screening technology that have increased their efficiency.

26 Jul 2024

Researchers Discover Genes Key to Spitting Cobra Venom's Cytotoxicity

Functional genomics to dissect and understand the cytotoxicity of spitting cobra venom and define the genetic interactions between the venom and the target to develop a locally acting antidote.

25 Jul 2024

New RNA Sequencing Dataset Reveals Genetic Diversity Across Global Populations

An open-access dataset of RNA sequences from lymphoblastoid cell lines of 731 individuals spanning 26 populations and five continental groups.

24 Jul 2024

Study Shows the Ability of Protein 'Signatures' to Predict Onset of 67 Diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

24 Jul 2024

New Model Reveals Interplay Between Circadian Rhythms and Sleep-Wake Cycles in Gene Expression

A mathematical, driven, damped harmonic oscillator model to assess the varying contributions of circadian cues and sleep-wake processes on gene expression and the rhythmic transcriptome.

18 Jul 2024

AI-Driven Atlas Reveals Hidden Proteins in Cellular Condensates

Scientists at the University of Cambridge have developed an atlas of proteins describing how they behave inside human cells.

11 Jul 2024

Harnessing Proteomics For Food Safety: Allergen Profiling and Food Authenticity Verification

The proteomics-based strategies used to profile food allergies and authenticate food products.

10 Jul 2024

A New Tool to Unravel the Mysteries of Metabolic Genes

A novel discovery platform has been created by a multidisciplinary research team to investigate the role of genes involved in metabolism, which is the culmination of all chemical reactions necessary for life.

9 Jul 2024

Unveiling the Role of Exons in Protein Foldability and Evolution

A new study led by Rice University's Peter Wolynes offers new insights into the evolution of foldable proteins. The research was published in the Proceedings of the National Academy of Sciences.

4 Jul 2024